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38 Publications


2022 | Journal Article | IST-REx-ID: 12261 | OA
Angermayr A, Pang TY, Chevereau G, Mitosch K, Lercher MJ, Bollenbach MT. Growth‐mediated negative feedback shapes quantitative antibiotic response. Molecular Systems Biology. 2022;18(9). doi:10.15252/msb.202110490
[Published Version] View | Files available | DOI | WoS
 

2019 | Journal Article | IST-REx-ID: 7026 | OA
Lukacisin M, Bollenbach MT. Emergent gene expression responses to drug combinations predict higher-order drug interactions. Cell Systems. 2019;9(5):423-433.e1-e3. doi:10.1016/j.cels.2019.10.004
[Published Version] View | Files available | DOI | WoS
 

2019 | Thesis | IST-REx-ID: 6392 | OA
Lukacisin M. Quantitative investigation of gene expression principles through combinatorial drug perturbation and theory. 2019. doi:10.15479/AT:ISTA:6392
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2018 | Thesis | IST-REx-ID: 6263 | OA
Lukacisinova M. Genetic determinants of antibiotic resistance evolution. 2018. doi:10.15479/AT:ISTA:th1072
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 520
Du W, Angermayr A, Jongbloets J, et al. Nonhierarchical flux regulation exposes the fitness burden associated with lactate production in Synechocystis sp. PCC6803. ACS Synthetic Biology. 2017;6(3):395-401. doi:10.1021/acssynbio.6b00235
View | DOI | PubMed | Europe PMC
 

2017 | Research Data Reference | IST-REx-ID: 9849
Lukacisinova M, Novak S, Paixao T. Modelling and simulation details. 2017. doi:10.1371/journal.pcbi.1005609.s001
[Published Version] View | Files available | DOI
 

2017 | Research Data Reference | IST-REx-ID: 9850
Lukacisinova M, Novak S, Paixao T. Extensions of the model. 2017. doi:10.1371/journal.pcbi.1005609.s002
[Published Version] View | Files available | DOI
 

2017 | Research Data Reference | IST-REx-ID: 9851
Lukacisinova M, Novak S, Paixao T. Heuristic prediction for multiple stresses. 2017. doi:10.1371/journal.pcbi.1005609.s003
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2017 | Research Data Reference | IST-REx-ID: 9852
Lukacisinova M, Novak S, Paixao T. Resistance frequencies for different combination strategies. 2017. doi:10.1371/journal.pcbi.1005609.s004
[Published Version] View | Files available | DOI
 

2017 | Thesis | IST-REx-ID: 818 | OA
Mitosch K. Timing, variability and cross-protection in bacteria – insights from dynamic gene expression responses to antibiotics. 2017. doi:10.15479/AT:ISTA:th_862
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 666 | OA
Mitosch K, Rieckh G, Bollenbach MT. Noisy response to antibiotic stress predicts subsequent single cell survival in an acidic environment. Cell Systems. 2017;4(4):393-403. doi:10.1016/j.cels.2017.03.001
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 822 | OA
de Vos M, Zagórski MP, Mcnally A, Bollenbach MT. Interaction networks, ecological stability, and collective antibiotic tolerance in polymicrobial infections. PNAS. 2017;114(40):10666-10671. doi:10.1073/pnas.1713372114
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 

2017 | Research Data | IST-REx-ID: 5563 | OA
Lukacisin M. MATLAB analysis code for “Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast.” 2017. doi:10.15479/AT:ISTA:64
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 1029 | OA
Lukacisin M, Landon M, Jajoo R. Sequence-specific thermodynamic properties of nucleic acids influence both transcriptional pausing and backtracking in yeast. PLoS One. 2017;12(3). doi:10.1371/journal.pone.0174066
[Published Version] View | Files available | DOI | WoS
 

2017 | Journal Article | IST-REx-ID: 696 | OA
Lukacisinova M, Novak S, Paixao T. Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. PLoS Computational Biology. 2017;13(7). doi:10.1371/journal.pcbi.1005609
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 1027 | OA
Lukacisinova M, Bollenbach MT. Toward a quantitative understanding of antibiotic resistance evolution. Current Opinion in Biotechnology. 2017;46:90-97. doi:10.1016/j.copbio.2017.02.013
[Published Version] View | Files available | DOI | WoS
 

2016 | Journal Article | IST-REx-ID: 1154 | OA
Schwarz J, Bierbaum V, Merrin J, et al. A microfluidic device for measuring cell migration towards substrate bound and soluble chemokine gradients. Scientific Reports. 2016;6. doi:10.1038/srep36440
[Published Version] View | Files available | DOI
 

2016 | Journal Article | IST-REx-ID: 1218 | OA
Angermayr A, Van Alphen P, Hasdemir D, et al. Culturing synechocystis sp. Strain pcc 6803 with N2 and CO2 in a diel regime reveals multiphase glycogen dynamics with low maintenance costs. Applied and Environmental Microbiology. 2016;82(14):4180-4189. doi:10.1128/AEM.00256-16
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2016 | Journal Article | IST-REx-ID: 1552 | OA
Qi Q, Toll Riera M, Heilbron K, Preston G, Maclean RC. The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa. Proceedings of the Royal Society of London Series B Biological Sciences. 2016;283(1822). doi:10.1098/rspb.2015.2452
[Published Version] View | Files available | DOI
 

2016 | Research Data | IST-REx-ID: 5556 | OA
Lukacisin M, Landon M, Jajoo R. MATLAB analysis code for “Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast.” 2016. doi:10.15479/AT:ISTA:45
[Published Version] View | Files available | DOI
 

2015 | Journal Article | IST-REx-ID: 1571
de Vos M, Dawid A, Šunderlíková V, Tans S. Breaking evolutionary constraint with a tradeoff ratchet. PNAS. 2015;112(48):14906-14911. doi:10.1073/pnas.1510282112
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2015 | Journal Article | IST-REx-ID: 1581
Bollenbach MT, Heisenberg C-PJ. Gradients are shaping up. Cell. 2015;161(3):431-432. doi:10.1016/j.cell.2015.04.009
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2015 | Journal Article | IST-REx-ID: 1586
Angermayr A, Gorchs A, Hellingwerf K. Metabolic engineering of cyanobacteria for the synthesis of commodity products. Trends in Biotechnology. 2015;33(6):352-361. doi:10.1016/j.tibtech.2015.03.009
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2015 | Journal Article | IST-REx-ID: 1623 | OA
Hammar P, Angermayr A, Sjostrom S, et al. Single-cell screening of photosynthetic growth and lactate production by cyanobacteria. Biotechnology for Biofuels. 2015;8(1). doi:10.1186/s13068-015-0380-2
[Published Version] View | Files available | DOI
 

2015 | Journal Article | IST-REx-ID: 1810 | OA
Bollenbach MT. Antimicrobial interactions: Mechanisms and implications for drug discovery and resistance evolution. Current Opinion in Microbiology. 2015;27:1-9. doi:10.1016/j.mib.2015.05.008
[Published Version] View | Files available | DOI
 

2015 | Journal Article | IST-REx-ID: 1823 | OA
Chevereau G, Bollenbach MT. Systematic discovery of drug interaction mechanisms. Molecular Systems Biology. 2015;11(4). doi:10.15252/msb.20156098
[Published Version] View | Files available | DOI
 

2015 | Research Data Reference | IST-REx-ID: 9711
Chevereau G, Lukacisinova M, Batur T, et al. Excel file containing the raw data for all figures. 2015. doi:10.1371/journal.pbio.1002299.s001
[Published Version] View | Files available | DOI
 

2015 | Research Data Reference | IST-REx-ID: 9765
Chevereau G, Lukacisinova M, Batur T, et al. Gene ontology enrichment analysis for the most sensitive gene deletion strains for all drugs. 2015. doi:10.1371/journal.pbio.1002299.s008
[Published Version] View | Files available | DOI
 

2015 | Journal Article | IST-REx-ID: 1509 | OA
Michalko J, Lukacisinova M, Bollenbach MT, Friml J. Embryo-lethal phenotypes in early abp1 mutants are due to disruption of the neighboring BSM gene. F1000 Research . 2015;4. doi:10.12688/f1000research.7143.1
[Published Version] View | Files available | DOI
 

2015 | Journal Article | IST-REx-ID: 1619 | OA
Chevereau G, Lukacisinova M, Batur T, et al. Quantifying the determinants of evolutionary dynamics leading to drug resistance. PLoS Biology. 2015;13(11). doi:10.1371/journal.pbio.1002299
[Published Version] View | Files available | DOI
 

2014 | Journal Article | IST-REx-ID: 2040 | OA
Kicheva A, Bollenbach MT, Ribeiro A, et al. Coordination of progenitor specification and growth in mouse and chick spinal cord. Science. 2014;345(6204). doi:10.1126/science.1254927
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2014 | Journal Article | IST-REx-ID: 2220 | OA
de Vos M, Bollenbach MT. Suppressive drug interactions between antifungals. Chemistry and Biology. 2014;21(4):439-440. doi:10.1016/j.chembiol.2014.04.004
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2014 | Journal Article | IST-REx-ID: 2001
Mitosch K, Bollenbach MT. Bacterial responses to antibiotics and their combinations. Environmental Microbiology Reports. 2014;6(6):545-557. doi:10.1111/1758-2229.12190
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2013 | Journal Article | IST-REx-ID: 2810 | OA
de Vos M, Poelwijk F, Battich N, Ndika J, Tans S. Environmental dependence of genetic constraint. PLoS Genetics. 2013;9(6). doi:10.1371/journal.pgen.1003580
[Published Version] View | Files available | DOI
 

2012 | Journal Article | IST-REx-ID: 2970
Kicheva A, Bollenbach MT, Wartlick O, Julicher F, Gonzalez Gaitan M. Investigating the principles of morphogen gradient formation: from tissues to cells. Current Opinion in Genetics & Development. 2012;22(6):527-532. doi:10.1016/j.gde.2012.08.004
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2012 | Journal Article | IST-REx-ID: 3160
Pantazis P, Bollenbach MT. Transcription factor kinetics and the emerging asymmetry in the early mammalian embryo. Cell Cycle. 2012;11(11):2055-2058. doi:10.4161/cc.20118
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2011 | Journal Article | IST-REx-ID: 3429
Plachta N, Bollenbach MT, Pease S, Fraser S, Pantazis P. Oct4 kinetics predict cell lineage patterning in the early mammalian embryo. Nature Cell Biology. 2011;13(2):117-123. doi:10.1038/ncb2154
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2011 | Journal Article | IST-REx-ID: 3376 | OA
Bollenbach MT, Kishony R. Resolution of gene regulatory conflicts caused by combinations of antibiotics. Molecular Cell. 2011;42(4):413-425. doi:10.1016/j.molcel.2011.04.016
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