Please note that ISTA Research Explorer no longer supports Internet Explorer versions 8 or 9 (or earlier).

We recommend upgrading to the latest Internet Explorer, Google Chrome, or Firefox.

111 Publications


2022 | Journal Article | IST-REx-ID: 10703 | OA
Gaertner F, Reis-Rodrigues P, de Vries I, Hons M, Aguilera J, Riedl M, Leithner AF, Tasciyan S, Kopf A, Merrin J, Zheden V, Kaufmann W, Hauschild R, Sixt MK. 2022. WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues. Developmental Cell. 57(1), 47–62.e9.
View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2022 | Journal Article | IST-REx-ID: 11588 | OA
Nicolai L, Kaiser R, Escaig R, Hoffknecht ML, Anjum A, Leunig A, Pircher J, Ehrlich A, Lorenz M, Ishikawa-Ankerhold H, Aird WC, Massberg S, Gärtner FR. 2022. Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains in vitro and in vivo. Haematologica. 107(7), 1669–1680.
View | Files available | DOI
 

2022 | Journal Article | IST-REx-ID: 9794 | OA
Assen FP, Abe J, Hons M, Hauschild R, Shamipour S, Kaufmann W, Costanzo T, Krens G, Brown M, Ludewig B, Hippenmeyer S, Heisenberg C-PJ, Weninger W, Hannezo EB, Luther SA, Stein JV, Sixt MK. 2022. Multitier mechanics control stromal adaptations in swelling lymph nodes. Nature Immunology.
View | Files available | DOI
 

2022 | Journal Article | IST-REx-ID: 11843 | OA
Tomasek K, Leithner AF, Glatzová I, Lukesch MS, Guet CC, Sixt MK. 2022. Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. eLife. 11, e78995.
View | Files available | DOI
 

2022 | Journal Article | IST-REx-ID: 12085 | OA
Mulla Y, Avellaneda Sarrió M, Roland A, Baldauf L, Jung W, Kim T, Tans SJ, Koenderink GH. 2022. Weak catch bonds make strong networks. Nature Materials. 21(9), 1019–1023.
View | DOI | Download Preprint (ext.)
 

2021 | Journal Article | IST-REx-ID: 10834 | OA
Stahnke S, Döring H, Kusch C, de Gorter DJJ, Dütting S, Guledani A, Pleines I, Schnoor M, Sixt MK, Geffers R, Rohde M, Müsken M, Kage F, Steffen A, Faix J, Nieswandt B, Rottner K, Stradal TEB. 2021. Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion. Current Biology. 31(10), 2051–2064.e8.
View | DOI | Download Preprint (ext.) | PubMed | Europe PMC
 

2021 | Journal Article | IST-REx-ID: 9259 | OA
Vaahtomeri K, Moussion C, Hauschild R, Sixt MK. 2021. Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium. Frontiers in Immunology. 12, 630002.
View | Files available | DOI | PubMed | Europe PMC
 

2021 | Thesis | IST-REx-ID: 10307
Tomasek K. 2021. Pathogenic Escherichia coli hijack the host immune response. IST Austria.
View | Files available | DOI
 

2021 | Journal Article | IST-REx-ID: 9429 | OA
Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev GA, Nicolas A, Sommer CM, Kreuzinger C, Dotter C, Knaus L, Dobler Z, Cacci E, Schur FK, Danzl JG, Novarino G. 2021. Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nature Communications. 12(1), 3058.
View | Files available | DOI
 

2021 | Journal Article | IST-REx-ID: 9094 | OA
Leithner AF, Altenburger L, Hauschild R, Assen FP, Rottner K, TEB S, Diz-Muñoz A, Stein J, Sixt MK. 2021. Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse. Journal of Cell Biology. 220(4), e202006081.
View | Files available | DOI | PubMed | Europe PMC
 

2021 | Journal Article | IST-REx-ID: 8988 | OA
Düllberg CF, Auer A, Canigova N, Loibl K, Loose M. 2021. In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1. PNAS. 118(1), e2010054118.
View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2021 | Journal Article | IST-REx-ID: 9294 | OA
Gärtner FR, Sixt MK. 2021. Engaging the front wheels to drive through fibrous terrain. Developmental Cell. 56(6), 723–725.
View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2021 | Preprint | IST-REx-ID: 10316 | OA
Tomasek K, Leithner AF, Glatzová I, Lukesch MS, Guet CC, Sixt MK. Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. bioRxiv, 10.1101/2021.10.18.464770.
View | Files available | DOI | Download Preprint (ext.)
 

2021 | Journal Article | IST-REx-ID: 9822 | OA
Zisis T, Schwarz J, Balles M, Kretschmer M, Nemethova M, Chait RP, Hauschild R, Lange J, Guet CC, Sixt MK, Zahler S. 2021. Sequential and switchable patterning for studying cellular processes under spatiotemporal control. ACS Applied Materials and Interfaces. 13(30), 35545–35560.
View | Files available | DOI | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 7875 | OA
Kopf A, Renkawitz J, Hauschild R, Girkontaite I, Tedford K, Merrin J, Thorn-Seshold O, Trauner D, Häcker H, Fischer KD, Kiermaier E, Sixt MK. 2020. Microtubules control cellular shape and coherence in amoeboid migrating cells. The Journal of Cell Biology. 219(6), e201907154.
View | Files available | DOI | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 7876 | OA
Sixt MK, Lämmermann T. 2020. T cells: Bridge-and-channel commute to the white pulp. Immunity. 52(5), 721–723.
View | DOI | Download Published Version (ext.)
 

2020 | Journal Article | IST-REx-ID: 7885
REVERSAT A, Gärtner FR, Merrin J, Stopp JA, Tasciyan S, Aguilera Servin JL, de Vries I, Hauschild R, Hons M, Piel M, Callan-Jones A, Voituriez R, Sixt MK. 2020. Cellular locomotion using environmental topography. Nature. 582, 582–585.
View | Files available | DOI
 

2020 | Journal Article | IST-REx-ID: 7909 | OA
Damiano-Guercio J, Kurzawa L, Müller J, Dimchev GA, Schaks M, Nemethova M, Pokrant T, Brühmann S, Linkner J, Blanchoin L, Sixt MK, Rottner K, Faix J. 2020. Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion. eLife. 9, e55351.
View | Files available | DOI
 

2020 | Journal Article | IST-REx-ID: 8132
Salzer E, Zoghi S, Kiss MG, Kage F, Rashkova C, Stahnke S, Haimel M, Platzer R, Caldera M, Ardy RC, Hoeger B, Block J, Medgyesi D, Sin C, Shahkarami S, Kain R, Ziaee V, Hammerl P, Bock C, Menche J, Dupré L, Huppa JB, Sixt MK, Lomakin A, Rottner K, Binder CJ, Stradal TEB, Rezaei N, Boztug K. 2020. The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Science Immunology. 5(49), eabc3979.
View | DOI | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 8142 | OA
Montesinos López JC, Abuzeineh A, Kopf A, Juanes Garcia A, Ötvös K, Petrášek J, Sixt MK, Benková E. 2020. Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage. The Embo Journal. 39(17), e104238.
View | Files available | DOI | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 7234 | OA
Obeidy P, Ju LA, Oehlers SH, Zulkhernain NS, Lee Q, Galeano Niño JL, Kwan RYQ, Tikoo S, Cavanagh LL, Mrass P, Cook AJL, Jackson SP, Biro M, Roediger B, Sixt MK, Weninger W. 2020. Partial loss of actin nucleator actin-related protein 2/3 activity triggers blebbing in primary T lymphocytes. Immunology and Cell Biology. 98(2), 93–113.
View | Files available | DOI | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 7623 | OA
Jankowiak G, Peurichard D, REVERSAT A, Schmeiser C, Sixt MK. 2020. Modeling adhesion-independent cell migration. Mathematical Models and Methods in Applied Sciences. 30(3), 513–537.
View | DOI | Download Preprint (ext.) | arXiv
 

2020 | Journal Article | IST-REx-ID: 8787 | OA
Nicolai L, Schiefelbein K, Lipsky S, Leunig A, Hoffknecht M, Pekayvaz K, Raude B, Marx C, Ehrlich A, Pircher J, Zhang Z, Saleh I, Marel A-K, Löf A, Petzold T, Lorenz M, Stark K, Pick R, Rosenberger G, Weckbach L, Uhl B, Xia S, Reichel CA, Walzog B, Schulz C, Zheden V, Bender M, Li R, Massberg S, Gärtner FR. 2020. Vascular surveillance by haptotactic blood platelets in inflammation and infection. Nature Communications. 11, 5778.
View | Files available | DOI | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 8190 | OA
Sixt MK, Huttenlocher A. 2020. Zena Werb (1945-2020): Cell biology in context. The Journal of cell biology. 219(8), e202007029.
View | Files available | DOI
 

2019 | Journal Article | IST-REx-ID: 6979
Kopf A, Sixt MK. 2019. Gut homeostasis: Active migration of intestinal epithelial cells in tissue renewal. Current Biology. 29(20), R1091–R1093.
View | DOI | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 6988
Nicolai L, Gärtner FR, Massberg S. 2019. Platelets in host defense: Experimental and clinical insights. Trends in Immunology. 40(10), 922–938.
View | DOI | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 7009
Yamada K, Sixt MK. 2019. Mechanisms of 3D cell migration. Nature Reviews Molecular Cell Biology. 20(12), 738–752.
View | DOI | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 7105 | OA
Yolland L, Burki M, Marcotti S, Luchici A, Kenny FN, Davis JR, Serna-Morales E, Müller J, Sixt MK, Davidson A, Wood W, Schumacher LJ, Endres RG, Miodownik M, Stramer BM. 2019. Persistent and polarized global actin flow is essential for directionality during cell migration. Nature Cell Biology. 21(11), 1370–1381.
View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 7404 | OA
Stürner T, Tatarnikova A, Müller J, Schaffran B, Cuntz H, Zhang Y, Nemethova M, Bogdan S, Small V, Tavosanis G. 2019. Transient localization of the Arp2/3 complex initiates neuronal dendrite branching in vivo. Development. 146(7), dev171397.
View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 7420 | OA
Sahgal P, Alanko JH, Icha J, Paatero I, Hamidi H, Arjonen A, Pietilä M, Rokka A, Ivaska J. 2019. GGA2 and RAB13 promote activity-dependent β1-integrin recycling. Journal of Cell Science. 132(11), jcs233387.
View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 6824
Gärtner FR, Massberg S. 2019. Patrolling the vascular borders: Platelets in immunity to infection and cancer. Nature Reviews Immunology. 19(12), 747–760.
View | DOI | PubMed | Europe PMC
 

2019 | Thesis | IST-REx-ID: 6891 | OA
Kopf A. 2019. The implication of cytoskeletal dynamics on leukocyte migration. IST Austria.
View | Files available | DOI
 

2019 | Journal Article | IST-REx-ID: 6328 | OA
Renkawitz J, Kopf A, Stopp JA, de Vries I, Driscoll MK, Merrin J, Hauschild R, Welf ES, Danuser G, Fiolka R, Sixt MK. 2019. Nuclear positioning facilitates amoeboid migration along the path of least resistance. Nature. 568, 546–550.
View | Files available | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 6877
Kopf A, Sixt MK. 2019. The neural crest pitches in to remove apoptotic debris. Cell. 179(1), 51–53.
View | Files available | DOI | PubMed | Europe PMC
 

2019 | Thesis | IST-REx-ID: 6947 | OA
Assen FP. 2019. Lymph node mechanics: Deciphering the interplay between stroma contractility, morphology and lymphocyte trafficking. IST Austria.
View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 308 | OA
Ratheesh A, Biebl J, Smutny M, Veselá J, Papusheva E, Krens G, Kaufmann W, György A, Casano AM, Siekhaus DE. 2018. Drosophila TNF modulates tissue tension in the embryo to facilitate macrophage invasive migration. Developmental Cell. 45(3), 331–346.
View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 318 | OA
Casano AM, Sixt MK. 2018. A fat lot of good for wound healing. Developmental Cell. 44(4), 405–406.
View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 5672 | OA
REVERSAT A, Sixt MK. 2018. IgM’s exit route. Journal of Experimental Medicine. 215(12), 2959–2961.
View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 5858 | OA
Hross S, Theis FJ, Sixt MK, Hasenauer J. 2018. Mechanistic description of spatial processes using integrative modelling of noise-corrupted imaging data. Journal of the Royal Society Interface. 15(149), 20180600.
View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 5861 | OA
Alanko JH, Sixt MK. 2018. The cell sets the tone. eLife. 7, e37888.
View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 5984 | OA
Morri M, Sanchez-Romero I, Tichy A-M, Kainrath S, Gerrard EJ, Hirschfeld P, Schwarz J, Janovjak HL. 2018. Optical functionalization of human class A orphan G-protein-coupled receptors. Nature Communications. 9(1), 1950.
View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 5992 | OA
Dolati S, Kage F, Mueller J, Müsken M, Kirchner M, Dittmar G, Sixt MK, Rottner K, Falcke M. 2018. On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility. Molecular Biology of the Cell. 29(22), 2674–2686.
View | Files available | DOI | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 6354 | OA
Fan S, Lorenz M, Massberg S, Gärtner FR. 2018. Platelet migration and bacterial trapping assay under flow. Bio-Protocol. 8(18), e3018.
View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 6497 | OA
Moalli F, Ficht X, Germann P, Vladymyrov M, Stolp B, de Vries I, Lyck R, Balmer J, Fiocchi A, Kreutzfeldt M, Merkler D, Iannacone M, Ariga A, Stoffel MH, Sharpe J, Bähler M, Sixt MK, Diz-Muñoz A, Stein JV. 2018. The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+T cells. The Journal of Experimental Medicine. 2015(7), 1869–1890.
View | Files available | DOI
 

2018 | Book Chapter | IST-REx-ID: 153
Renkawitz J, REVERSAT A, Leithner AF, Merrin J, Sixt MK. 2018.Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments. In: Methods in Cell Biology. vol. 147, 79–91.
View | DOI | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 275 | OA
Brown M, Johnson L, Leone D, Májek P, Vaahtomeri K, Senfter D, Bukosza N, Schachner H, Asfour G, Langer B, Hauschild R, Parapatics K, Hong Y, Bennett K, Kain R, Detmar M, Sixt MK, Jackson D, Kerjaschki D. 2018. Lymphatic exosomes promote dendritic cell migration along guidance cues. Journal of Cell Biology. 217(6), 2205–2221.
View | Files available | DOI | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 276 | OA
Frick C, Dettinger P, Renkawitz J, Jauch A, Berger C, Recher M, Schroeder T, Mehling M. 2018. Nano-scale microfluidics to study 3D chemotaxis at the single cell level. PLoS One. 13(6), e0198330.
View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 437 | OA
Leithner AF, Renkawitz J, de Vries I, Hauschild R, Haecker H, Sixt MK. 2018. Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration. European Journal of Immunology. 48(6), 1074–1077.
View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 15 | OA
Hons M, Kopf A, Hauschild R, Leithner AF, Gärtner FR, Abe J, Renkawitz J, Stein J, Sixt MK. 2018. Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells. Nature Immunology. 19(6), 606–616.
View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 402 | OA
Brown M, Assen FP, Leithner AF, Abe J, Schachner H, Asfour G, Bagó Horváth Z, Stein J, Uhrin P, Sixt MK, Kerjaschki D. 2018. Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice. Science. 359(6382), 1408–1411.
View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 

Filters and Search Terms

department=MiSi

Search

Filter Publications