Please note that ISTA Research Explorer no longer supports Internet Explorer versions 8 or 9 (or earlier).
We recommend upgrading to the latest Internet Explorer, Google Chrome, or Firefox.
110 Publications
2017 | Research Data | IST-REx-ID: 5567 |

Immunological synapse DC-Tcells
A.F. Leithner, (2017).
View
| Files available
| DOI
A.F. Leithner, (2017).
2017 | Journal Article | IST-REx-ID: 569 |

Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments
F. Spira, S. Cuylen Haering, S. Mehta, M. Samwer, A. REVERSAT, A. Verma, R. Oldenbourg, M.K. Sixt, D. Gerlich, ELife 6 (2017).
View
| Files available
| DOI
F. Spira, S. Cuylen Haering, S. Mehta, M. Samwer, A. REVERSAT, A. Verma, R. Oldenbourg, M.K. Sixt, D. Gerlich, ELife 6 (2017).
2017 | Journal Article | IST-REx-ID: 571
Migrating platelets are mechano scavengers that collect and bundle bacteria
Gärtner FR, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher R, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt MK, Massberg S. 2017. Migrating platelets are mechano scavengers that collect and bundle bacteria. Cell Press. 171(6), 1368–1382.
View
| DOI
Gärtner FR, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher R, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt MK, Massberg S. 2017. Migrating platelets are mechano scavengers that collect and bundle bacteria. Cell Press. 171(6), 1368–1382.
2017 | Journal Article | IST-REx-ID: 727
Load adaptation of lamellipodial actin networks
J. Mueller, G. Szep, M. Nemethova, I. de Vries, A. Lieber, C. Winkler, K. Kruse, J. Small, C. Schmeiser, K. Keren, R. Hauschild, M.K. Sixt, Cell 171 (2017) 188–200.
View
| DOI
J. Mueller, G. Szep, M. Nemethova, I. de Vries, A. Lieber, C. Winkler, K. Kruse, J. Small, C. Schmeiser, K. Keren, R. Hauschild, M.K. Sixt, Cell 171 (2017) 188–200.
2017 | Journal Article | IST-REx-ID: 1161
Cell migration: Making the waves
J. Müller, M.K. Sixt, Current Biology 27 (2017) R24–R25.
View
| DOI
J. Müller, M.K. Sixt, Current Biology 27 (2017) R24–R25.
2017 | Journal Article | IST-REx-ID: 659 |

FMNL formins boost lamellipodial force generation
F. Kage, M. Winterhoff, V. Dimchev, J. Müller, T. Thalheim, A. Freise, S. Brühmann, J. Kollasser, J. Block, G.A. Dimchev, M. Geyer, H. Schnittler, C. Brakebusch, T. Stradal, M. Carlier, M.K. Sixt, J. Käs, J. Faix, K. Rottner, Nature Communications 8 (2017).
View
| Files available
| DOI
F. Kage, M. Winterhoff, V. Dimchev, J. Müller, T. Thalheim, A. Freise, S. Brühmann, J. Kollasser, J. Block, G.A. Dimchev, M. Geyer, H. Schnittler, C. Brakebusch, T. Stradal, M. Carlier, M.K. Sixt, J. Käs, J. Faix, K. Rottner, Nature Communications 8 (2017).
2017 | Journal Article | IST-REx-ID: 668 |

Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion
M. Horsthemke, A. Bachg, K. Groll, S. Moyzio, B. Müther, S. Hemkemeyer, R. Wedlich Söldner, M.K. Sixt, S. Tacke, M. Bähler, P. Hanley, Journal of Biological Chemistry 292 (2017) 7258–7273.
View
| Files available
| DOI
M. Horsthemke, A. Bachg, K. Groll, S. Moyzio, B. Müther, S. Hemkemeyer, R. Wedlich Söldner, M.K. Sixt, S. Tacke, M. Bähler, P. Hanley, Journal of Biological Chemistry 292 (2017) 7258–7273.
2017 | Journal Article | IST-REx-ID: 672 |

Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. de Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
View
| Files available
| DOI
K. Vaahtomeri, M. Brown, R. Hauschild, I. de Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
2017 | Journal Article | IST-REx-ID: 674
Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. de Vries, A.F. Leithner, A. REVERSAT, J. Merrin, T. Tarrant, M.T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
View
| DOI
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. de Vries, A.F. Leithner, A. REVERSAT, J. Merrin, T. Tarrant, M.T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
2017 | Journal Article | IST-REx-ID: 677 |

The INO80 complex removes H2A.Z to promote presynaptic filament formation during homologous recombination
C. Lademann, J. Renkawitz, B. Pfander, S. Jentsch, Cell Reports 19 (2017) 1294–1303.
View
| Files available
| DOI
C. Lademann, J. Renkawitz, B. Pfander, S. Jentsch, Cell Reports 19 (2017) 1294–1303.
2017 | Journal Article | IST-REx-ID: 679 |

The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection
F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.
View
| DOI
| Download Submitted Version (ext.)
| PubMed | Europe PMC
F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.
2017 | Journal Article | IST-REx-ID: 694 |

A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity
A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.
View
| Files available
| DOI
| PubMed | Europe PMC
A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.
2017 | Journal Article | IST-REx-ID: 664
The dynamic cytokine niche
F.P. Assen, M.K. Sixt, Immunity 46 (2017) 519–520.
View
| Files available
| DOI
F.P. Assen, M.K. Sixt, Immunity 46 (2017) 519–520.
2016 | Thesis | IST-REx-ID: 1129 |

Quantitative analysis of haptotactic cell migration
J. Schwarz, Quantitative Analysis of Haptotactic Cell Migration, IST Austria, 2016.
View
| Files available
J. Schwarz, Quantitative Analysis of Haptotactic Cell Migration, IST Austria, 2016.
2016 | Journal Article | IST-REx-ID: 1137 |

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics
Salzer E, Çaǧdaş D, Hons M, Mace E, Garncarz W, Petronczki O, Platzer R, Pfajfer L, Bilic I, Ban S, Willmann K, Mukherjee M, Supper V, Hsu H, Banerjee P, Sinha P, Mcclanahan F, Zlabinger G, Pickl W, Gribben J, Stockinger H, Bennett K, Huppa J, Dupré L, Sanal Ö, Jäger U, Sixt MK, Tezcan I, Orange J, Boztug K. 2016. RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics. Nature Immunology. 17(12), 1352–1360.
View
| DOI
| Download Submitted Version (ext.)
| PubMed | Europe PMC
Salzer E, Çaǧdaş D, Hons M, Mace E, Garncarz W, Petronczki O, Platzer R, Pfajfer L, Bilic I, Ban S, Willmann K, Mukherjee M, Supper V, Hsu H, Banerjee P, Sinha P, Mcclanahan F, Zlabinger G, Pickl W, Gribben J, Stockinger H, Bennett K, Huppa J, Dupré L, Sanal Ö, Jäger U, Sixt MK, Tezcan I, Orange J, Boztug K. 2016. RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics. Nature Immunology. 17(12), 1352–1360.
2016 | Journal Article | IST-REx-ID: 1142 |

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
Martins R, Maier J, Gorki A, Huber K, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger M, Radic Sarikas B, Lardeau C, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth S, Decker T, Bennett K, Kubicek S, Sixt MK, Superti Furga G, Knapp S. 2016. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nature Immunology. 17(12), 1361–1372.
View
| DOI
| Download Submitted Version (ext.)
Martins R, Maier J, Gorki A, Huber K, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger M, Radic Sarikas B, Lardeau C, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth S, Decker T, Bennett K, Kubicek S, Sixt MK, Superti Furga G, Knapp S. 2016. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nature Immunology. 17(12), 1361–1372.
2016 | Journal Article | IST-REx-ID: 1150
A Radical Break Restraining Neutrophil Migration
J. Renkawitz, M.K. Sixt, Developmental Cell 38 (2016) 448–450.
View
| DOI
J. Renkawitz, M.K. Sixt, Developmental Cell 38 (2016) 448–450.
2016 | Journal Article | IST-REx-ID: 1154 |

A microfluidic device for measuring cell migration towards substrate bound and soluble chemokine gradients
J. Schwarz, V. Bierbaum, J. Merrin, T. Frank, R. Hauschild, M.T. Bollenbach, S. Tay, M.K. Sixt, M. Mehling, Scientific Reports 6 (2016).
View
| Files available
| DOI
J. Schwarz, V. Bierbaum, J. Merrin, T. Frank, R. Hauschild, M.T. Bollenbach, S. Tay, M.K. Sixt, M. Mehling, Scientific Reports 6 (2016).
2016 | Journal Article | IST-REx-ID: 1597
Quantitative analysis of dendritic cell haptotaxis
J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.
View
| DOI
| PubMed | Europe PMC
J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.
2016 | Journal Article | IST-REx-ID: 1599 |

Polysialylation controls dendritic cell trafficking by regulating chemokine recognition
E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190.
View
| DOI
| Download Submitted Version (ext.)
| PubMed | Europe PMC
E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190.