Metabolism of glutamate and ammonia in astrocyte an immunocytochemical study

T. Kaneko, R. Shigemoto, N. Mizuno, Brain Research 457 (1988) 160–164.

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Abstract
Alpha-ketoglutamate (α-KG) reductive amination activity in rat brain was found to be mostly absorbed with an antibody against liver glutamate dehydrogenase. With this and anti-glutamine synthetase antibodies, α-KG reductive amination activity was immunocytochemically shown to coexist with glutamine synthetase activity in astrocytes. The results suggest that astrocytes de novo synthesize glutamate from α-KG and ammonia, and metabolize it to glutamine.
Publishing Year
Date Published
1988-08-02
Journal Title
Brain Research
Volume
457
Issue
1
Page
160 - 164
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Kaneko T, Shigemoto R, Mizuno N. Metabolism of glutamate and ammonia in astrocyte an immunocytochemical study. Brain Research. 1988;457(1):160-164. doi:10.1016/0006-8993(88)90069-8
Kaneko, T., Shigemoto, R., & Mizuno, N. (1988). Metabolism of glutamate and ammonia in astrocyte an immunocytochemical study. Brain Research, 457(1), 160–164. https://doi.org/10.1016/0006-8993(88)90069-8
Kaneko, Takeshi, Ryuichi Shigemoto, and Noboru Mizuno. “Metabolism of Glutamate and Ammonia in Astrocyte an Immunocytochemical Study.” Brain Research 457, no. 1 (1988): 160–64. https://doi.org/10.1016/0006-8993(88)90069-8.
T. Kaneko, R. Shigemoto, and N. Mizuno, “Metabolism of glutamate and ammonia in astrocyte an immunocytochemical study,” Brain Research, vol. 457, no. 1, pp. 160–164, 1988.
Kaneko T, Shigemoto R, Mizuno N. 1988. Metabolism of glutamate and ammonia in astrocyte an immunocytochemical study. Brain Research. 457(1), 160–164.
Kaneko, Takeshi, et al. “Metabolism of Glutamate and Ammonia in Astrocyte an Immunocytochemical Study.” Brain Research, vol. 457, no. 1, Elsevier, 1988, pp. 160–64, doi:10.1016/0006-8993(88)90069-8.

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