---
_id: '922'
abstract:
- lang: eng
text: 'We study theoretically the morphologies of biological tubes affected by various
pathologies. When epithelial cells grow, the negative tension produced by their
division provokes a buckling instability. Several shapes are investigated: varicose,
dilated, sinuous, or sausagelike. They are all found in pathologies of tracheal,
renal tubes, or arteries. The final shape depends crucially on the mechanical
parameters of the tissues: Young''s modulus, wall-to-lumen ratio, homeostatic
pressure. We argue that since tissues must be in quasistatic mechanical equilibrium,
abnormal shapes convey information as to what causes the pathology. We calculate
a phase diagram of tubular instabilities which could be a helpful guide for investigating
the underlying genetic regulation.'
article_processing_charge: No
author:
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Jacques
full_name: Prost, Jacques
last_name: Prost
- first_name: Jean
full_name: Joanny, Jean
last_name: Joanny
citation:
ama: Hannezo EB, Prost J, Joanny J. Mechanical instabilities of biological tubes.
Physical Review Letters. 2012;109(1). doi:10.1103/PhysRevLett.109.018101
apa: Hannezo, E. B., Prost, J., & Joanny, J. (2012). Mechanical instabilities
of biological tubes. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.109.018101
chicago: Hannezo, Edouard B, Jacques Prost, and Jean Joanny. “Mechanical Instabilities
of Biological Tubes.” Physical Review Letters. American Physical Society,
2012. https://doi.org/10.1103/PhysRevLett.109.018101.
ieee: E. B. Hannezo, J. Prost, and J. Joanny, “Mechanical instabilities of biological
tubes,” Physical Review Letters, vol. 109, no. 1. American Physical Society,
2012.
ista: Hannezo EB, Prost J, Joanny J. 2012. Mechanical instabilities of biological
tubes. Physical Review Letters. 109(1).
mla: Hannezo, Edouard B., et al. “Mechanical Instabilities of Biological Tubes.”
Physical Review Letters, vol. 109, no. 1, American Physical Society, 2012,
doi:10.1103/PhysRevLett.109.018101.
short: E.B. Hannezo, J. Prost, J. Joanny, Physical Review Letters 109 (2012).
date_created: 2018-12-11T11:49:13Z
date_published: 2012-07-03T00:00:00Z
date_updated: 2021-01-12T08:21:56Z
day: '03'
doi: 10.1103/PhysRevLett.109.018101
extern: '1'
external_id:
arxiv:
- '1207.1516'
intvolume: ' 109'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1207.1516
month: '07'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '6519'
status: public
title: Mechanical instabilities of biological tubes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 109
year: '2012'
...