{"type":"journal_article","doi":"10.1103/PhysRevLett.107.078104","_id":"918","language":[{"iso":"eng"}],"acknowledgement":"We thank S. Fre and M. Huygue for discussion and for showing us in vivo samples and A. Bergès for help with the manuscript.","publication":"Physical Review Letters","publication_status":"published","issue":"7","author":[{"full_name":"Hannezo, Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6005-1561","first_name":"Edouard B","last_name":"Hannezo"},{"full_name":"Prost, Jacques","last_name":"Prost","first_name":"Jacques"},{"full_name":"Joanny, Jean","last_name":"Joanny","first_name":"Jean"}],"status":"public","date_created":"2018-12-11T11:49:11Z","volume":107,"abstract":[{"text":"We study theoretically the shapes of a dividing epithelial monolayer of cells lying on top of an elastic stroma. The negative tension created by cell division provokes a buckling instability at a finite wave vector leading to the formation of periodic arrays of villi and crypts. The instability is similar to the buckling of a metallic plate under compression. We use the results to rationalize the various structures of the intestinal lining observed in vivo. Taking into account the coupling between cell division and local curvature, we obtain different patterns of villi and crypts, which could explain the different morphologies of the small intestine and the colon.","lang":"eng"}],"publist_id":"6521","date_updated":"2021-01-12T08:21:54Z","oa_version":"None","year":"2011","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"08","day":"11","publisher":"American Physical Society","title":"Instabilities of monolayered epithelia Shape and structure of villi and crypts","date_published":"2011-08-11T00:00:00Z","extern":"1","citation":{"chicago":"Hannezo, Edouard B, Jacques Prost, and Jean Joanny. “Instabilities of Monolayered Epithelia Shape and Structure of Villi and Crypts.” <i>Physical Review Letters</i>. American Physical Society, 2011. <a href=\"https://doi.org/10.1103/PhysRevLett.107.078104\">https://doi.org/10.1103/PhysRevLett.107.078104</a>.","ista":"Hannezo EB, Prost J, Joanny J. 2011. Instabilities of monolayered epithelia Shape and structure of villi and crypts. Physical Review Letters. 107(7).","apa":"Hannezo, E. B., Prost, J., &#38; Joanny, J. (2011). Instabilities of monolayered epithelia Shape and structure of villi and crypts. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.107.078104\">https://doi.org/10.1103/PhysRevLett.107.078104</a>","mla":"Hannezo, Edouard B., et al. “Instabilities of Monolayered Epithelia Shape and Structure of Villi and Crypts.” <i>Physical Review Letters</i>, vol. 107, no. 7, American Physical Society, 2011, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.107.078104\">10.1103/PhysRevLett.107.078104</a>.","short":"E.B. Hannezo, J. Prost, J. Joanny, Physical Review Letters 107 (2011).","ama":"Hannezo EB, Prost J, Joanny J. Instabilities of monolayered epithelia Shape and structure of villi and crypts. <i>Physical Review Letters</i>. 2011;107(7). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.107.078104\">10.1103/PhysRevLett.107.078104</a>","ieee":"E. B. Hannezo, J. Prost, and J. Joanny, “Instabilities of monolayered epithelia Shape and structure of villi and crypts,” <i>Physical Review Letters</i>, vol. 107, no. 7. American Physical Society, 2011."},"intvolume":"       107"}