The evolution of gene duplications: Classifying and distinguishing between models

H. Innan, F. Kondrashov, Nature Reviews Genetics 11 (2010) 97–108.

Download
No fulltext has been uploaded. References only!

Journal Article | Published
Author
Abstract
Gene duplications and their subsequent divergence play an important part in the evolution of novel gene functions. Several models for the emergence, maintenance and evolution of gene copies have been proposed. However, a clear consensus on how gene duplications are fixed and maintained in genomes is lacking. Here, we present a comprehensive classification of the models that are relevant to all stages of the evolution of gene duplications. Each model predicts a unique combination of evolutionary dynamics and functional properties. Setting out these predictions is an important step towards identifying the main mechanisms that are involved in the evolution of gene duplications.
Publishing Year
Date Published
2010-02-01
Journal Title
Nature Reviews Genetics
Acknowledgement
We thank M. Lynch for insightful comments on the manuscript.
Volume
11
Issue
2
Page
97 - 108
IST-REx-ID

Cite this

Innan H, Kondrashov F. The evolution of gene duplications: Classifying and distinguishing between models. Nature Reviews Genetics. 2010;11(2):97-108. doi:10.1038/nrg2689
Innan, H., & Kondrashov, F. (2010). The evolution of gene duplications: Classifying and distinguishing between models. Nature Reviews Genetics, 11(2), 97–108. https://doi.org/10.1038/nrg2689
Innan, Hideki, and Fyodor Kondrashov. “The Evolution of Gene Duplications: Classifying and Distinguishing between Models.” Nature Reviews Genetics 11, no. 2 (2010): 97–108. https://doi.org/10.1038/nrg2689.
H. Innan and F. Kondrashov, “The evolution of gene duplications: Classifying and distinguishing between models,” Nature Reviews Genetics, vol. 11, no. 2, pp. 97–108, 2010.
Innan H, Kondrashov F. 2010. The evolution of gene duplications: Classifying and distinguishing between models. Nature Reviews Genetics. 11(2), 97–108.
Innan, Hideki, and Fyodor Kondrashov. “The Evolution of Gene Duplications: Classifying and Distinguishing between Models.” Nature Reviews Genetics, vol. 11, no. 2, Nature Publishing Group, 2010, pp. 97–108, doi:10.1038/nrg2689.

Export

Marked Publications

Open Data IST Research Explorer

Search this title in

Google Scholar