{"issue":"22","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2020-09-18T10:14:05Z","language":[{"iso":"eng"}],"date_published":"2005-05-14T00:00:00Z","article_processing_charge":"No","author":[{"id":"7B541462-FAF6-11E9-A490-E8DFE5697425","last_name":"Schanda","orcid":"0000-0002-9350-7606","full_name":"Schanda, Paul","first_name":"Paul"},{"last_name":"Brutscher","first_name":"Bernhard","full_name":"Brutscher, Bernhard"}],"publication_status":"published","day":"14","title":"Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds","publisher":"American Chemical Society","intvolume":"       127","doi":"10.1021/ja051306e","extern":"1","_id":"8492","abstract":[{"lang":"eng","text":"We demonstrate for different protein samples that 2D 1H−15N correlation NMR spectra can be recorded in a few seconds of acquisition time using a new band-selective optimized flip-angle short-transient heteronuclear multiple quantum coherence experiment. This has enabled us to measure fast hydrogen−deuterium exchange rate constants along the backbone of a small globular protein fragment by real-time 2D NMR."}],"quality_controlled":"1","keyword":["Colloid and Surface Chemistry","Biochemistry","General Chemistry","Catalysis"],"date_updated":"2021-01-12T08:19:39Z","type":"journal_article","status":"public","publication_identifier":{"issn":["0002-7863","1520-5126"]},"article_type":"original","month":"05","publication":"Journal of the American Chemical Society","year":"2005","volume":127,"citation":{"ieee":"P. Schanda and B. Brutscher, “Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds,” <i>Journal of the American Chemical Society</i>, vol. 127, no. 22. American Chemical Society, pp. 8014–8015, 2005.","mla":"Schanda, Paul, and Bernhard Brutscher. “Very Fast Two-Dimensional NMR Spectroscopy for Real-Time Investigation of Dynamic Events in Proteins on the Time Scale of Seconds.” <i>Journal of the American Chemical Society</i>, vol. 127, no. 22, American Chemical Society, 2005, pp. 8014–15, doi:<a href=\"https://doi.org/10.1021/ja051306e\">10.1021/ja051306e</a>.","ista":"Schanda P, Brutscher B. 2005. Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds. Journal of the American Chemical Society. 127(22), 8014–8015.","ama":"Schanda P, Brutscher B. Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds. <i>Journal of the American Chemical Society</i>. 2005;127(22):8014-8015. doi:<a href=\"https://doi.org/10.1021/ja051306e\">10.1021/ja051306e</a>","apa":"Schanda, P., &#38; Brutscher, B. (2005). Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds. <i>Journal of the American Chemical Society</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/ja051306e\">https://doi.org/10.1021/ja051306e</a>","short":"P. Schanda, B. Brutscher, Journal of the American Chemical Society 127 (2005) 8014–8015.","chicago":"Schanda, Paul, and Bernhard Brutscher. “Very Fast Two-Dimensional NMR Spectroscopy for Real-Time Investigation of Dynamic Events in Proteins on the Time Scale of Seconds.” <i>Journal of the American Chemical Society</i>. American Chemical Society, 2005. <a href=\"https://doi.org/10.1021/ja051306e\">https://doi.org/10.1021/ja051306e</a>."},"oa_version":"None","page":"8014-8015"}