--- res: bibo_abstract: - Directional transport of the phytohormone auxin is a versatile, plant-specific mechanism regulating many aspects of plant development. The recently identified plant hormones, strigolactones (SLs), are implicated in many plant traits; among others, they modify the phenotypic output of PIN-FORMED (PIN) auxin transporters for fine-tuning of growth and developmental responses. Here, we show in pea and Arabidopsis that SLs target processes dependent on the canalization of auxin flow, which involves auxin feedback on PIN subcellular distribution. D14 receptor- and MAX2 F-box-mediated SL signaling inhibits the formation of auxin-conducting channels after wounding or from artificial auxin sources, during vasculature de novo formation and regeneration. At the cellular level, SLs interfere with auxin effects on PIN polar targeting, constitutive PIN trafficking as well as clathrin-mediated endocytosis. Our results identify a non-transcriptional mechanism of SL action, uncoupling auxin feedback on PIN polarity and trafficking, thereby regulating vascular tissue formation and regeneration.@eng bibo_authorlist: - foaf_Person: foaf_givenName: J foaf_name: Zhang, J foaf_surname: Zhang - foaf_Person: foaf_givenName: E foaf_name: Mazur, E foaf_surname: Mazur - foaf_Person: foaf_givenName: J foaf_name: Balla, J foaf_surname: Balla - foaf_Person: foaf_givenName: Michelle C foaf_name: Gallei, Michelle C foaf_surname: Gallei foaf_workInfoHomepage: http://www.librecat.org/personId=35A03822-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0003-1286-7368 - foaf_Person: foaf_givenName: P foaf_name: Kalousek, P foaf_surname: Kalousek - foaf_Person: foaf_givenName: Z foaf_name: Medveďová, Z foaf_surname: Medveďová - foaf_Person: foaf_givenName: Y foaf_name: Li, Y foaf_surname: Li - foaf_Person: foaf_givenName: Y foaf_name: Wang, Y foaf_surname: Wang - foaf_Person: foaf_givenName: Tomas foaf_name: Prat, Tomas foaf_surname: Prat foaf_workInfoHomepage: http://www.librecat.org/personId=3DA3BFEE-F248-11E8-B48F-1D18A9856A87 - foaf_Person: foaf_givenName: Mina K foaf_name: Vasileva, Mina K foaf_surname: Vasileva foaf_workInfoHomepage: http://www.librecat.org/personId=3407EB18-F248-11E8-B48F-1D18A9856A87 - foaf_Person: foaf_givenName: V foaf_name: Reinöhl, V foaf_surname: Reinöhl - foaf_Person: foaf_givenName: S foaf_name: Procházka, S foaf_surname: Procházka - foaf_Person: foaf_givenName: R foaf_name: Halouzka, R foaf_surname: Halouzka - foaf_Person: foaf_givenName: P foaf_name: Tarkowski, P foaf_surname: Tarkowski - foaf_Person: foaf_givenName: C foaf_name: Luschnig, C foaf_surname: Luschnig - foaf_Person: foaf_givenName: PB foaf_name: Brewer, PB foaf_surname: Brewer - foaf_Person: foaf_givenName: Jiří foaf_name: Friml, Jiří foaf_surname: Friml foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0002-8302-7596 bibo_doi: 10.1038/s41467-020-17252-y bibo_issue: '1' bibo_volume: 11 dct_date: 2020^xs_gYear dct_identifier: - UT:000550062200004 dct_isPartOf: - http://id.crossref.org/issn/2041-1723 dct_language: eng dct_publisher: Springer Nature@ dct_title: Strigolactones inhibit auxin feedback on PIN-dependent auxin transport canalization@ fabio_hasPubmedId: '32665554' ...