[{"isi":1,"has_accepted_license":"1","day":"01","publication":"PLoS Computational Biology","dc":{"publisher":["Public Library of Science"],"type":["info:eu-repo/semantics/article","doc-type:article","text","http://purl.org/coar/resource_type/c_6501"],"date":["2019"],"identifier":["https://research-explorer.ista.ac.at/record/7103","https://research-explorer.ista.ac.at/download/7103/7104"],"description":["Origin and functions of intermittent transitions among sleep stages, including short awakenings and arousals, constitute a challenge to the current homeostatic framework for sleep regulation, focusing on factors modulating sleep over large time scales. Here we propose that the complex micro-architecture characterizing the sleep-wake cycle results from an underlying non-equilibrium critical dynamics, bridging collective behaviors across spatio-temporal scales. We investigate θ and δ wave dynamics in control rats and in rats with lesions of sleep-promoting neurons in the parafacial zone. We demonstrate that intermittent bursts in θ and δ rhythms exhibit a complex temporal organization, with long-range power-law correlations and a robust duality of power law (θ-bursts, active phase) and exponential-like (δ-bursts, quiescent phase) duration distributions, typical features of non-equilibrium systems self-organizing at criticality. Crucially, such temporal organization relates to anti-correlated coupling between θ- and δ-bursts, and is independent of the dominant physiologic state and lesions, a solid indication of a basic principle in sleep dynamics."],"relation":["info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pcbi.1007268","info:eu-repo/semantics/altIdentifier/issn/1553-7358","info:eu-repo/semantics/altIdentifier/wos/000500976100014","info:eu-repo/semantics/altIdentifier/pmid/31725712","info:eu-repo/grantAgreement/EC/H2020/754411"],"source":["Wang JWJL, Lombardi F, Zhang X, Anaclet C, Ivanov PC. Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture. PLoS Computational Biology. 2019;15(11). doi:10.1371/journal.pcbi.1007268"],"title":["Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture"],"subject":["ddc:570","ddc:000"],"language":["eng"],"rights":["info:eu-repo/semantics/openAccess"],"creator":["Wang, Jilin W. J. L.","Lombardi, Fabrizio","Zhang, Xiyun","Anaclet, Christelle","Ivanov, Plamen Ch."]},"uri_base":"https://research-explorer.ista.ac.at","date_published":"2019-11-01T00:00:00Z","date_created":"2019-11-25T08:20:47Z","quality_controlled":"1","oa":1,"dini_type":"doc-type:article","citation":{"ista":"Wang JWJL, Lombardi F, Zhang X, Anaclet C, Ivanov PC. 2019. Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture. PLoS Computational Biology. 15(11), e1007268.","chicago":"Wang, Jilin W. J. L., Fabrizio Lombardi, Xiyun Zhang, Christelle Anaclet, and Plamen Ch. Ivanov. “Non-Equilibrium Critical Dynamics of Bursts in θ and δ Rhythms as Fundamental Characteristic of Sleep and Wake Micro-Architecture.” PLoS Computational Biology. Public Library of Science, 2019. https://doi.org/10.1371/journal.pcbi.1007268.","ieee":"J. W. J. L. Wang, F. Lombardi, X. Zhang, C. Anaclet, and P. C. Ivanov, “Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture,” PLoS Computational Biology, vol. 15, no. 11. Public Library of Science, 2019.","short":"J.W.J.L. Wang, F. Lombardi, X. Zhang, C. Anaclet, P.C. Ivanov, PLoS Computational Biology 15 (2019).","apa":"Wang, J. W. J. L., Lombardi, F., Zhang, X., Anaclet, C., & Ivanov, P. C. (2019). Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture. PLoS Computational Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1007268","mla":"Wang, Jilin W. J. L., et al. “Non-Equilibrium Critical Dynamics of Bursts in θ and δ Rhythms as Fundamental Characteristic of Sleep and Wake Micro-Architecture.” PLoS Computational Biology, vol. 15, no. 11, e1007268, Public Library of Science, 2019, doi:10.1371/journal.pcbi.1007268."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Jilin W. J. L.","last_name":"Wang"},{"first_name":"Fabrizio","id":"A057D288-3E88-11E9-986D-0CF4E5697425","last_name":"Lombardi","orcid":"0000-0003-2623-5249"},{"last_name":"Zhang","first_name":"Xiyun"},{"last_name":"Anaclet","first_name":"Christelle"},{"first_name":"Plamen Ch.","last_name":"Ivanov"}],"external_id":{"pmid":[],"isi":[]},"article_processing_charge":"No","article_number":"e1007268","project":[{"name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"publication_identifier":{"issn":[]},"publication_status":"published","file":[{"file_id":"7104","checksum":"2a096a9c6dcc6eaa94077b2603bc6c12","content_type":"application/pdf","access_level":"open_access","relation":"main_file","date_created":"2019-11-25T08:24:01Z","file_name":"2019_PLOSComBio_Wang.pdf","date_updated":"2020-07-14T12:47:49Z","file_size":3982516,"creator":"dernst"}],"language":[{}],"volume":15,"issue":"11","ec_funded":1,"abstract":[{"lang":"eng"}],"oa_version":"Published Version","pmid":1,"scopus_import":"1","month":"11","intvolume":" 15","date_updated":"2023-10-17T12:30:07Z","creator":{"login":"dernst","id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},"ddc":[],"file_date_updated":"2020-07-14T12:47:49Z","department":[{"tree":[{"_id":"ResearchGroups"},{"_id":"IST"}],"_id":"GaTk"}],"_id":"7103","type":"journal_article","article_type":"original","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public"}]