--- res: bibo_abstract: - "A process of restorative patterning in plant roots correctly replaces eliminated cells to heal local injuries despite the absence of cell migration, which underpins wound healing in animals. \r\n\r\nPatterning in plants relies on oriented cell divisions and acquisition of specific cell identities. Plants regularly endure wounds caused by abiotic or biotic environmental stimuli and have developed extraordinary abilities to restore their tissues after injuries. Here, we provide insight into a mechanism of restorative patterning that repairs tissues after wounding. Laser-assisted elimination of different cells in Arabidopsis root combined with live-imaging tracking during vertical growth allowed analysis of the regeneration processes in vivo. Specifically, the cells adjacent to the inner side of the injury re-activated their stem cell transcriptional programs. They accelerated their progression through cell cycle, coordinately changed the cell division orientation, and ultimately acquired de novo the correct cell fates to replace missing cells. These observations highlight existence of unknown intercellular positional signaling and demonstrate the capability of specified cells to re-acquire stem cell programs as a crucial part of the plant-specific mechanism of wound healing.@eng" bibo_authorlist: - foaf_Person: foaf_givenName: Petra foaf_name: Marhavá, Petra foaf_surname: Marhavá foaf_workInfoHomepage: http://www.librecat.org/personId=44E59624-F248-11E8-B48F-1D18A9856A87 - foaf_Person: foaf_givenName: Lukas foaf_name: Hörmayer, Lukas foaf_surname: Hörmayer foaf_workInfoHomepage: http://www.librecat.org/personId=2EEE7A2A-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0001-8295-2926 - foaf_Person: foaf_givenName: Saiko foaf_name: Yoshida, Saiko foaf_surname: Yoshida foaf_workInfoHomepage: http://www.librecat.org/personId=2E46069C-F248-11E8-B48F-1D18A9856A87 - foaf_Person: foaf_givenName: Peter foaf_name: Marhavy, Peter foaf_surname: Marhavy foaf_workInfoHomepage: http://www.librecat.org/personId=3F45B078-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0001-5227-5741 - foaf_Person: foaf_givenName: Eva foaf_name: Benková, Eva foaf_surname: Benková foaf_workInfoHomepage: http://www.librecat.org/personId=38F4F166-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0002-8510-9739 - foaf_Person: foaf_givenName: Jiří foaf_name: Friml, Jiří foaf_surname: Friml foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0002-8302-7596 bibo_doi: 10.1016/j.cell.2019.04.015 bibo_issue: '4' bibo_volume: 177 dct_date: 2019^xs_gYear dct_identifier: - UT:000466843000015 dct_isPartOf: - http://id.crossref.org/issn/00928674 - http://id.crossref.org/issn/10974172 dct_language: eng dct_publisher: Elsevier@ dct_title: Re-activation of stem cell pathways for pattern restoration in plant wound healing@ fabio_hasPubmedId: '31051107' ...