{"article_type":"original","abstract":[{"text":"We theoretically study the shapes of lipid vesicles confined to a spherical cavity, elaborating a framework based on the so-called limiting shapes constructed from geometrically simple structural elements such as double-membrane walls and edges. Partly inspired by numerical results, the proposed non-compartmentalized and compartmentalized limiting shapes are arranged in the bilayer-couple phase diagram which is then compared to its free-vesicle counterpart. We also compute the area-difference-elasticity phase diagram of the limiting shapes and we use it to interpret shape transitions experimentally observed in vesicles confined within another vesicle. The limiting-shape framework may be generalized to theoretically investigate the structure of certain cell organelles such as the mitochondrion.","lang":"eng"}],"intvolume":"        15","file":[{"file_size":5370762,"content_type":"application/pdf","file_name":"lmt_sftmtr_V8.pdf","access_level":"open_access","file_id":"8641","relation":"main_file","success":1,"creator":"bkavcic","date_created":"2020-10-09T11:00:05Z","checksum":"614c337d6424ccd3d48d1b1f9513510d","date_updated":"2020-10-09T11:00:05Z"}],"date_updated":"2021-01-12T08:03:41Z","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","issue":"4","_id":"5817","publisher":"Royal Society of Chemistry","tmp":{"short":"CC BY-NC-ND (3.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode","image":"/images/cc_by_nc_nd.png"},"volume":15,"file_date_updated":"2020-10-09T11:00:05Z","date_created":"2019-01-11T07:37:47Z","pmid":1,"status":"public","type":"journal_article","month":"01","language":[{"iso":"eng"}],"day":"10","publication_identifier":{"issn":["1744-683X","1744-6848"]},"ddc":["530"],"doi":"10.1039/c8sm01956h","date_published":"2019-01-10T00:00:00Z","author":[{"orcid":"0000-0001-6041-254X","id":"350F91D2-F248-11E8-B48F-1D18A9856A87","first_name":"Bor","full_name":"Kavcic, Bor","last_name":"Kavcic"},{"full_name":"Sakashita, A.","first_name":"A.","last_name":"Sakashita"},{"last_name":"Noguchi","full_name":"Noguchi, H.","first_name":"H."},{"last_name":"Ziherl","first_name":"P.","full_name":"Ziherl, P."}],"article_processing_charge":"No","external_id":{"pmid":["30629082"]},"department":[{"_id":"GaTk"}],"title":"Limiting shapes of confined lipid vesicles","has_accepted_license":"1","publication_status":"published","license":"https://creativecommons.org/licenses/by-nc-nd/3.0/","page":"602-614","oa_version":"Submitted Version","year":"2019","scopus_import":"1","citation":{"ieee":"B. Kavcic, A. Sakashita, H. Noguchi, and P. Ziherl, “Limiting shapes of confined lipid vesicles,” <i>Soft Matter</i>, vol. 15, no. 4. Royal Society of Chemistry, pp. 602–614, 2019.","short":"B. Kavcic, A. Sakashita, H. Noguchi, P. Ziherl, Soft Matter 15 (2019) 602–614.","chicago":"Kavcic, Bor, A. Sakashita, H. Noguchi, and P. Ziherl. “Limiting Shapes of Confined Lipid Vesicles.” <i>Soft Matter</i>. Royal Society of Chemistry, 2019. <a href=\"https://doi.org/10.1039/c8sm01956h\">https://doi.org/10.1039/c8sm01956h</a>.","apa":"Kavcic, B., Sakashita, A., Noguchi, H., &#38; Ziherl, P. (2019). Limiting shapes of confined lipid vesicles. <i>Soft Matter</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/c8sm01956h\">https://doi.org/10.1039/c8sm01956h</a>","ista":"Kavcic B, Sakashita A, Noguchi H, Ziherl P. 2019. Limiting shapes of confined lipid vesicles. Soft Matter. 15(4), 602–614.","mla":"Kavcic, Bor, et al. “Limiting Shapes of Confined Lipid Vesicles.” <i>Soft Matter</i>, vol. 15, no. 4, Royal Society of Chemistry, 2019, pp. 602–14, doi:<a href=\"https://doi.org/10.1039/c8sm01956h\">10.1039/c8sm01956h</a>.","ama":"Kavcic B, Sakashita A, Noguchi H, Ziherl P. Limiting shapes of confined lipid vesicles. <i>Soft Matter</i>. 2019;15(4):602-614. doi:<a href=\"https://doi.org/10.1039/c8sm01956h\">10.1039/c8sm01956h</a>"},"oa":1,"publication":"Soft Matter"}