--- res: bibo_abstract: - During epithelial tissue development, repair, and homeostasis, adherens junctions (AJs) ensure intercellular adhesion and tissue integrity while allowing for cell and tissue dynamics. Mechanical forces play critical roles in AJs’ composition and dynamics. Recent findings highlight that beyond a well-established role in reinforcing cell-cell adhesion, AJ mechanosensitivity promotes junctional remodeling and polarization, thereby regulating critical processes such as cell intercalation, division, and collective migration. Here, we provide an integrated view of mechanosensing mechanisms that regulate cell-cell contact composition, geometry, and integrity under tension and highlight pivotal roles for mechanosensitive AJ remodeling in preserving epithelial integrity and sustaining tissue dynamics.@eng bibo_authorlist: - foaf_Person: foaf_givenName: Diana C foaf_name: Nunes Pinheiro, Diana C foaf_surname: Nunes Pinheiro foaf_workInfoHomepage: http://www.librecat.org/personId=2E839F16-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0003-4333-7503 - foaf_Person: foaf_givenName: Yohanns foaf_name: Bellaïche, Yohanns foaf_surname: Bellaïche bibo_doi: 10.1016/j.devcel.2018.09.014 bibo_issue: '1' bibo_volume: 47 dct_date: 2018^xs_gYear dct_identifier: - UT:000446579900002 dct_language: eng dct_publisher: Cell Press@ dct_title: Mechanical force-driven adherents junction remodeling and epithelial dynamics@ ...