Evolution and multilevel optimization of the genetic code

Bollenbach MT, Vetsigian K, Kishony R. 2007. Evolution and multilevel optimization of the genetic code. Genome Research. 17(4), 401–404.

Download
No fulltext has been uploaded. References only!

Journal Article | Published | English
Author
Bollenbach, TobiasIST Austria ; Vetsigian, Kalin; Kishony, Roy
Abstract
The discovery of the genetic code was one of the most important advances of modern biology. But there is more to a DNA code than protein sequence; DNA carries signals for splicing, localization, folding, and regulation that are often embedded within the protein-coding sequence. In this issue, Itzkovitz and Alon show that the specific 64-to-20 mapping found in the genetic code may have been optimized for permitting protein-coding regions to carry this extra information and suggest that this property may have evolved as a side benefit of selection to minimize the negative effects of frameshift errors.
Publishing Year
Date Published
2007-03-09
Journal Title
Genome Research
Volume
17
Issue
4
Page
401 - 404
IST-REx-ID

Cite this

Bollenbach MT, Vetsigian K, Kishony R. Evolution and multilevel optimization of the genetic code. Genome Research. 2007;17(4):401-404. doi:10.1101/gr.6144007
Bollenbach, M. T., Vetsigian, K., & Kishony, R. (2007). Evolution and multilevel optimization of the genetic code. Genome Research. Cold Spring Harbor Laboratory Press. https://doi.org/10.1101/gr.6144007
Bollenbach, Mark Tobias, Kalin Vetsigian, and Roy Kishony. “Evolution and Multilevel Optimization of the Genetic Code.” Genome Research. Cold Spring Harbor Laboratory Press, 2007. https://doi.org/10.1101/gr.6144007.
M. T. Bollenbach, K. Vetsigian, and R. Kishony, “Evolution and multilevel optimization of the genetic code,” Genome Research, vol. 17, no. 4. Cold Spring Harbor Laboratory Press, pp. 401–404, 2007.
Bollenbach MT, Vetsigian K, Kishony R. 2007. Evolution and multilevel optimization of the genetic code. Genome Research. 17(4), 401–404.
Bollenbach, Mark Tobias, et al. “Evolution and Multilevel Optimization of the Genetic Code.” Genome Research, vol. 17, no. 4, Cold Spring Harbor Laboratory Press, 2007, pp. 401–04, doi:10.1101/gr.6144007.

Export

Marked Publications

Open Data IST Research Explorer

Search this title in

Google Scholar