--- res: bibo_abstract: - In the zebrafish, Danio rerio, a caudal and pectoral fin fold develop during embryogenesis. At larval stages the caudal fin fold is replaced by four different fins, the unpaired anal, dorsal and tail fins. In addition the paired pelvic fins are formed, We have identified a total of 118 mutations affecting larval fin formation, Mutations in 11 genes lead to abnormal morphology or degeneration of both caudal and pectoral fin folds, Most mutants survive to adulthood and form a surprisingly normal complement of adult fins, Mutations in nine genes result in an increased or reduced size of the pectoral fins, Interestingly, in mutants of one of these genes, dackel (dak), pectoral fin buds form initially, but later the fin epithelium fails to expand, Expression of sonic hedgehog mRNA in the posterior mesenchyme of the pectoral fin bud is initiated in dak embryos, but not maintained, Mutations in five other genes affect adult fin but not larval fin development, Two mutants, longfin (lof) and another longfin (alf) have generally longer fins. Stein und bein (sub) has reduced dorsal and pelvic fins, whereas finless (fls) and wanda (wan) mutants affect all adult fins, Finally, mutations in four genes causing defects in embryonic skin formation will be briefly reported.@eng bibo_authorlist: - foaf_Person: foaf_givenName: Fredericus foaf_name: Van Eeden, Fredericus foaf_surname: Van Eeden - foaf_Person: foaf_givenName: Michael foaf_name: Granato, Michael foaf_surname: Granato - foaf_Person: foaf_givenName: Ursula foaf_name: Schach, Ursula foaf_surname: Schach - foaf_Person: foaf_givenName: Michael foaf_name: Brand, Michael foaf_surname: Brand - foaf_Person: foaf_givenName: Makoto foaf_name: Furutani Seiki, Makoto foaf_surname: Furutani Seiki - foaf_Person: foaf_givenName: Pascal foaf_name: Haffter, Pascal foaf_surname: Haffter - foaf_Person: foaf_givenName: Matthias foaf_name: Hammerschmidt, Matthias foaf_surname: Hammerschmidt - foaf_Person: foaf_givenName: Carl-Philipp J foaf_name: Heisenberg, Carl-Philipp J foaf_surname: Heisenberg foaf_workInfoHomepage: http://www.librecat.org/personId=39427864-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0002-0912-4566 - foaf_Person: foaf_givenName: Yunjin foaf_name: Jiang, Yunjin foaf_surname: Jiang - foaf_Person: foaf_givenName: Donald foaf_name: Kane, Donald foaf_surname: Kane - foaf_Person: foaf_givenName: Robert foaf_name: Kelsh, Robert foaf_surname: Kelsh - foaf_Person: foaf_givenName: Mary foaf_name: Mullins, Mary foaf_surname: Mullins - foaf_Person: foaf_givenName: Jörg foaf_name: Odenthal, Jörg foaf_surname: Odenthal - foaf_Person: foaf_givenName: Rachel foaf_name: Warga, Rachel foaf_surname: Warga - foaf_Person: foaf_givenName: Christiane foaf_name: Nüsslein Volhard, Christiane foaf_surname: Nüsslein Volhard bibo_doi: '10.1242/dev.123.1.255 ' bibo_issue: '1' bibo_volume: 123 dct_date: 1996^xs_gYear dct_isPartOf: - http://id.crossref.org/issn/0950-1991 dct_language: eng dct_publisher: Company of Biologists@ dct_title: Genetic analysis of fin formation in the zebrafish, Danio rerio@ fabio_hasPubmedId: '9007245 ' ...