Back and forth between cell fate specification and movement during vertebrate gastrulation

Heisenberg C-PJ, Solnica Krezel L. 2008. Back and forth between cell fate specification and movement during vertebrate gastrulation. Current Opinion in Genetics & Development. 18(4), 311–316.

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Journal Article | Published | English
Author
Heisenberg, Carl-Philipp IST Austria ; Solnica Krezel, Lilianna
Abstract
Animal body plan arises during gastrulation and organogenesis by the coordination of inductive events and cell movements. Several signaling pathways, such as BMP, FGF, Hedgehog, Nodal, and Wnt have well-recognized instructive roles in cell fate specification during vertebrate embryogenesis. Growing evidence indicates that BMP, Nodal, and FGF signaling also regulate cell movements, and that they do so through mechanisms distinct from those that specify cell fates. Moreover, pathways controlling cell movements can also indirectly influence cell fate specification by regulating dimensions and relative positions of interacting tissues. The current challenge is to delineate the molecular mechanisms via which the major signaling pathways regulate cell fate specification and movements, and how these two processes are coordinated to ensure normal development.
Publishing Year
Date Published
2008-01-01
Journal Title
Current Opinion in Genetics & Development
Volume
18
Issue
4
Page
311 - 316
IST-REx-ID

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Heisenberg C-PJ, Solnica Krezel L. Back and forth between cell fate specification and movement during vertebrate gastrulation. Current Opinion in Genetics & Development. 2008;18(4):311-316. doi:10.1016/j.gde.2008.07.011
Heisenberg, C.-P. J., & Solnica Krezel, L. (2008). Back and forth between cell fate specification and movement during vertebrate gastrulation. Current Opinion in Genetics & Development. Elsevier. https://doi.org/10.1016/j.gde.2008.07.011
Heisenberg, Carl-Philipp J, and Lilianna Solnica Krezel. “Back and Forth between Cell Fate Specification and Movement during Vertebrate Gastrulation.” Current Opinion in Genetics & Development. Elsevier, 2008. https://doi.org/10.1016/j.gde.2008.07.011.
C.-P. J. Heisenberg and L. Solnica Krezel, “Back and forth between cell fate specification and movement during vertebrate gastrulation,” Current Opinion in Genetics & Development, vol. 18, no. 4. Elsevier, pp. 311–316, 2008.
Heisenberg C-PJ, Solnica Krezel L. 2008. Back and forth between cell fate specification and movement during vertebrate gastrulation. Current Opinion in Genetics & Development. 18(4), 311–316.
Heisenberg, Carl-Philipp J., and Lilianna Solnica Krezel. “Back and Forth between Cell Fate Specification and Movement during Vertebrate Gastrulation.” Current Opinion in Genetics & Development, vol. 18, no. 4, Elsevier, 2008, pp. 311–16, doi:10.1016/j.gde.2008.07.011.

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