A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics

Krieg M, Helenius J, Heisenberg C-PJ, Mueller D. 2008. A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics. Angewandte Chemie - International Edition. 47(50), 9775–9777.

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Journal Article | Published | English
Author
Krieg, Michael; Helenius, Jonne; Heisenberg, Carl-Philipp IST Austria ; Mueller, Daniel
Abstract
(Figure Presented) The name's Bond: Separated cells form membranous nanotubes whose tips are tethered by adhesive bonds (see picture). The lifetime of receptor-ligand interactions can be measured by using membrane nanotubes of living cells as constant force actuators. Because the nanotubes are extruded from living cells at conditions approaching the physiological, cellular processes can be both studied and utilized.
Publishing Year
Date Published
2008-12-01
Journal Title
Angewandte Chemie - International Edition
Volume
47
Issue
50
Page
9775 - 9777
IST-REx-ID

Cite this

Krieg M, Helenius J, Heisenberg C-PJ, Mueller D. A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics. Angewandte Chemie - International Edition. 2008;47(50):9775-9777. doi:10.1002/anie.200803552
Krieg, M., Helenius, J., Heisenberg, C.-P. J., & Mueller, D. (2008). A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics. Angewandte Chemie - International Edition. Wiley-Blackwell. https://doi.org/10.1002/anie.200803552
Krieg, Michael, Jonne Helenius, Carl-Philipp J Heisenberg, and Daniel Mueller. “A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics.” Angewandte Chemie - International Edition. Wiley-Blackwell, 2008. https://doi.org/10.1002/anie.200803552.
M. Krieg, J. Helenius, C.-P. J. Heisenberg, and D. Mueller, “A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics,” Angewandte Chemie - International Edition, vol. 47, no. 50. Wiley-Blackwell, pp. 9775–9777, 2008.
Krieg M, Helenius J, Heisenberg C-PJ, Mueller D. 2008. A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics. Angewandte Chemie - International Edition. 47(50), 9775–9777.
Krieg, Michael, et al. “A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics.” Angewandte Chemie - International Edition, vol. 47, no. 50, Wiley-Blackwell, 2008, pp. 9775–77, doi:10.1002/anie.200803552.

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