Wnt11/Pk1a-mediated planar cell polarity signalling orchestrates epithelial organ morphogenesis by regulating N-cadherin dependent cell adhesion forces
Oteíza P, Köppen M, Krieg M, Preibisch S, Haertel S, Müller D, Heisenberg C-PJ, Concha M. 2009. Wnt11/Pk1a-mediated planar cell polarity signalling orchestrates epithelial organ morphogenesis by regulating N-cadherin dependent cell adhesion forces. Mechanisms of Development. 126(Supplement 1), S80–S80.
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Journal Article
| Published
| English
Author
Oteíza, Pablo;
Köppen, Mathias;
Krieg, Michael;
Preibisch, Steffen;
Haertel, Steffen;
Müller, Daniel;
Heisenberg, Carl-Philipp ISTA 
;
Concha, Miguel
;
Concha, MiguelAbstract
Organ formation requires the precise assembly of progenitor cells into a functional unit. Mechanical forces are likely to play a critical role in this process, but it is unclear how these are molecularly controlled during development. Here, we show that Wnt11/ Pk1a-mediated planar cell polarity (PCP) signalling coordinates formation of the zebrafish laterality organ (Kupffer’s vesicle, KV) by regulating adhesion forces between organ progenitor cells (the dorsal forerunner cells, DFCs).
Publishing Year
Date Published
2009-08-05
Journal Title
Mechanisms of Development
Volume
126
Issue
Supplement 1
Page
S80 - S80
IST-REx-ID
Cite this
Oteíza P, Köppen M, Krieg M, et al. Wnt11/Pk1a-mediated planar cell polarity signalling orchestrates epithelial organ morphogenesis by regulating N-cadherin dependent cell adhesion forces. Mechanisms of Development. 2009;126(Supplement 1):S80-S80. doi:10.1016/j.mod.2009.06.098
Oteíza, P., Köppen, M., Krieg, M., Preibisch, S., Haertel, S., Müller, D., … Concha, M. (2009). Wnt11/Pk1a-mediated planar cell polarity signalling orchestrates epithelial organ morphogenesis by regulating N-cadherin dependent cell adhesion forces. Mechanisms of Development. Elsevier. https://doi.org/10.1016/j.mod.2009.06.098
Oteíza, Pablo, Mathias Köppen, Michael Krieg, Steffen Preibisch, Steffen Haertel, Daniel Müller, Carl-Philipp J Heisenberg, and Miguel Concha. “Wnt11/Pk1a-Mediated Planar Cell Polarity Signalling Orchestrates Epithelial Organ Morphogenesis by Regulating N-Cadherin Dependent Cell Adhesion Forces.” Mechanisms of Development. Elsevier, 2009. https://doi.org/10.1016/j.mod.2009.06.098.
P. Oteíza et al., “Wnt11/Pk1a-mediated planar cell polarity signalling orchestrates epithelial organ morphogenesis by regulating N-cadherin dependent cell adhesion forces,” Mechanisms of Development, vol. 126, no. Supplement 1. Elsevier, pp. S80–S80, 2009.
Oteíza P, Köppen M, Krieg M, Preibisch S, Haertel S, Müller D, Heisenberg C-PJ, Concha M. 2009. Wnt11/Pk1a-mediated planar cell polarity signalling orchestrates epithelial organ morphogenesis by regulating N-cadherin dependent cell adhesion forces. Mechanisms of Development. 126(Supplement 1), S80–S80.
Oteíza, Pablo, et al. “Wnt11/Pk1a-Mediated Planar Cell Polarity Signalling Orchestrates Epithelial Organ Morphogenesis by Regulating N-Cadherin Dependent Cell Adhesion Forces.” Mechanisms of Development, vol. 126, no. Supplement 1, Elsevier, 2009, pp. S80–S80, doi:10.1016/j.mod.2009.06.098.
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