--- _id: '4160' abstract: - lang: eng text: While the function of patterning in organogenesis is being extensively studied, considerably less is known of reverse effects that organ formation imposes on patterning. In zebrafish, the Kupffer’s vesicle (KV) and parapineal (PP) are embryonic struc- tures that share mechanisms of organogenesis and whose func- tion is essential for normal patterning along the left–right axis. Early morphogenesis of KV and PP organs involve the compaction of progenitor cells into a tight cluster within which three-dimen- sional cellular rosettes are formed. Organisation into rosettes pre- cedes the detachment of progenitor cells from neighbouring tissue and thus represents a key step towards organ formation. Such morphogenetic event is essential for organ function and its disruption has profound effects on left–right patterning. acknowledgement: 'Grant sponsors: HHMI, CONICYT (PBCT ACT47, PBCT Red6), ICM P04-048-F, EU FP6-2004-NEST-PATH EDCBNL, DAAD.' article_processing_charge: No author: - first_name: Pablo full_name: Oteíza, Pablo last_name: Oteíza - first_name: Carmen full_name: Lemus, Carmen last_name: Lemus - first_name: Mathias full_name: Köppen, Mathias last_name: Köppen - first_name: Karina full_name: Palma, Karina last_name: Palma - first_name: Michael full_name: Krieg, Michael last_name: Krieg - first_name: Cristina full_name: Melo, Cristina last_name: Melo - first_name: Cecilia full_name: Farias, Cecilia last_name: Farias - first_name: Eduardo full_name: Pulgar, Eduardo last_name: Pulgar - first_name: Steffen full_name: Preibisch, Steffen last_name: Preibisch - first_name: Steffen full_name: Hartel, Steffen last_name: Hartel - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 - first_name: Miguel full_name: Concha, Miguel last_name: Concha citation: ama: Oteíza P, Lemus C, Köppen M, et al. Linking organ formation to left-right patterning in the embryonic zebrafish. Mechanisms of Development. 2009;126(Supplement 1):S11-S11. doi:10.1016/j.mod.2009.06.970 apa: Oteíza, P., Lemus, C., Köppen, M., Palma, K., Krieg, M., Melo, C., … Concha, M. (2009). Linking organ formation to left-right patterning in the embryonic zebrafish. Mechanisms of Development. Elsevier. https://doi.org/10.1016/j.mod.2009.06.970 chicago: Oteíza, Pablo, Carmen Lemus, Mathias Köppen, Karina Palma, Michael Krieg, Cristina Melo, Cecilia Farias, et al. “Linking Organ Formation to Left-Right Patterning in the Embryonic Zebrafish.” Mechanisms of Development. Elsevier, 2009. https://doi.org/10.1016/j.mod.2009.06.970. ieee: P. Oteíza et al., “Linking organ formation to left-right patterning in the embryonic zebrafish,” Mechanisms of Development, vol. 126, no. Supplement 1. Elsevier, pp. S11–S11, 2009. ista: Oteíza P, Lemus C, Köppen M, Palma K, Krieg M, Melo C, Farias C, Pulgar E, Preibisch S, Hartel S, Heisenberg C-PJ, Concha M. 2009. Linking organ formation to left-right patterning in the embryonic zebrafish. Mechanisms of Development. 126(Supplement 1), S11–S11. mla: Oteíza, Pablo, et al. “Linking Organ Formation to Left-Right Patterning in the Embryonic Zebrafish.” Mechanisms of Development, vol. 126, no. Supplement 1, Elsevier, 2009, pp. S11–S11, doi:10.1016/j.mod.2009.06.970. short: P. Oteíza, C. Lemus, M. Köppen, K. Palma, M. Krieg, C. Melo, C. Farias, E. Pulgar, S. Preibisch, S. Hartel, C.-P.J. Heisenberg, M. Concha, Mechanisms of Development 126 (2009) S11–S11. date_created: 2018-12-11T12:07:18Z date_published: 2009-08-05T00:00:00Z date_updated: 2021-01-12T07:54:57Z day: '05' doi: 10.1016/j.mod.2009.06.970 extern: '1' intvolume: ' 126' issue: Supplement 1 language: - iso: eng month: '08' oa_version: None page: S11 - S11 publication: Mechanisms of Development publication_status: published publisher: Elsevier publist_id: '1959' status: public title: Linking organ formation to left-right patterning in the embryonic zebrafish type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 126 year: '2009' ...