Modeling network dynamics: the lac operon, a case study

J. Vilar, C.C. Guet, S. Leibler, Journal of Cell Biology 161 (2003) 471–476.


Journal Article | Published
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Abstract
We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description (molecular, cellular, and that of cell population) into a single model, which seems to capture many experimental aspects of the system.
Publishing Year
Date Published
2003-01-12
Journal Title
Journal of Cell Biology
Volume
161
Issue
3
Page
471 - 476
IST-REx-ID

Cite this

Vilar J, Guet CC, Leibler S. Modeling network dynamics: the lac operon, a case study. Journal of Cell Biology. 2003;161(3):471-476. doi:10.1083/jcb.200301125
Vilar, J., Guet, C. C., & Leibler, S. (2003). Modeling network dynamics: the lac operon, a case study. Journal of Cell Biology, 161(3), 471–476. https://doi.org/10.1083/jcb.200301125
Vilar, Jose, Calin C Guet, and Stanislas Leibler. “Modeling Network Dynamics: The Lac Operon, a Case Study.” Journal of Cell Biology 161, no. 3 (2003): 471–76. https://doi.org/10.1083/jcb.200301125.
J. Vilar, C. C. Guet, and S. Leibler, “Modeling network dynamics: the lac operon, a case study,” Journal of Cell Biology, vol. 161, no. 3, pp. 471–476, 2003.
Vilar J, Guet CC, Leibler S. 2003. Modeling network dynamics: the lac operon, a case study. Journal of Cell Biology. 161(3), 471–476.
Vilar, Jose, et al. “Modeling Network Dynamics: The Lac Operon, a Case Study.” Journal of Cell Biology, vol. 161, no. 3, Rockefeller University Press, 2003, pp. 471–76, doi:10.1083/jcb.200301125.

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