Decoding spike timing: The differential reverse-correlation method

Tkačik G, Magnasco M. 2008. Decoding spike timing: The differential reverse-correlation method. Biosystems. 93(1–2), 90–100.


Journal Article | Published
Author
Tkacik, GasperIST Austria ; Magnasco, Marcelo O
Abstract
It is widely acknowledged that detailed timing of action potentials is used to encode information, for example, in auditory pathways; however, the computational tools required to analyze encoding through timing are still in their infancy. We present a simple example of encoding, based on a recent model of time-frequency analysis, in which units fire action potentials when a certain condition is met, but the timing of the action potential depends also on other features of the stimulus. We show that, as a result, spike-triggered averages are smoothed so much that they do not represent the true features of the encoding. Inspired by this example, we present a simple method, differential reverse correlations, that can separate an analysis of what causes a neuron to spike, and what controls its timing. We analyze with this method the leaky integrate-and-fire neuron and show the method accurately reconstructs the model's kernel.
Publishing Year
Date Published
2008-07-01
Journal Title
Biosystems
Volume
93
Issue
1-2
Page
90 - 100
IST-REx-ID

Cite this

Tkačik G, Magnasco M. Decoding spike timing: The differential reverse-correlation method. Biosystems. 2008;93(1-2):90-100. doi:10.1016/j.biosystems.2008.04.011
Tkačik, G., & Magnasco, M. (2008). Decoding spike timing: The differential reverse-correlation method. Biosystems. Elsevier. https://doi.org/10.1016/j.biosystems.2008.04.011
Tkačik, Gašper, and Marcelo Magnasco. “Decoding Spike Timing: The Differential Reverse-Correlation Method.” Biosystems. Elsevier, 2008. https://doi.org/10.1016/j.biosystems.2008.04.011.
G. Tkačik and M. Magnasco, “Decoding spike timing: The differential reverse-correlation method,” Biosystems, vol. 93, no. 1–2. Elsevier, pp. 90–100, 2008.
Tkačik G, Magnasco M. 2008. Decoding spike timing: The differential reverse-correlation method. Biosystems. 93(1–2), 90–100.
Tkačik, Gašper, and Marcelo Magnasco. “Decoding Spike Timing: The Differential Reverse-Correlation Method.” Biosystems, vol. 93, no. 1–2, Elsevier, 2008, pp. 90–100, doi:10.1016/j.biosystems.2008.04.011.
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