--- _id: '3732' abstract: - lang: eng text: 'Ising models with pairwise interactions are the least structured, or maximum-entropy, probability distributions that exactly reproduce measured pairwise correlations between spins. Here we use this equivalence to construct Ising models that describe the correlated spiking activity of populations of 40 neurons in the salamander retina responding to natural movies. We show that pairwise interactions between neurons account for observed higher-order correlations, and that for groups of 10 or more neurons pairwise interactions can no longer be regarded as small perturbations in an independent system. We then construct network ensembles that generalize the network instances observed in the experiment, and study their thermodynamic behavior and coding capacity. Based on this construction, we can also create synthetic networks of 120 neurons, and find that with increasing size the networks operate closer to a critical point and start exhibiting collective behaviors reminiscent of spin glasses. We examine closely two such behaviors that could be relevant for neural code: tuning of the network to the critical point to maximize the ability to encode diverse stimuli, and using the metastable states of the Ising Hamiltonian as neural code words.' author: - first_name: Gasper full_name: Gasper Tkacik id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkacik orcid: 0000-0002-6699-1455 - first_name: Elad full_name: Schneidman, Elad last_name: Schneidman - first_name: Michael full_name: Berry, Michael J last_name: Berry - first_name: William full_name: Bialek, William S last_name: Bialek citation: ama: Tkačik G, Schneidman E, Berry M, Bialek W. Spin glass models for a network of real neurons. ArXiv. 2009;q-NC. apa: Tkačik, G., Schneidman, E., Berry, M., & Bialek, W. (2009). Spin glass models for a network of real neurons. ArXiv. ArXiv. chicago: Tkačik, Gašper, Elad Schneidman, Michael Berry, and William Bialek. “Spin Glass Models for a Network of Real Neurons.” ArXiv. ArXiv, 2009. ieee: G. Tkačik, E. Schneidman, M. Berry, and W. Bialek, “Spin glass models for a network of real neurons,” ArXiv, vol. q-NC. ArXiv, 2009. ista: Tkačik G, Schneidman E, Berry M, Bialek W. 2009. Spin glass models for a network of real neurons. ArXiv, q-NC, . mla: Tkačik, Gašper, et al. “Spin Glass Models for a Network of Real Neurons.” ArXiv, vol. q-NC, ArXiv, 2009. short: G. Tkačik, E. Schneidman, M. Berry, W. Bialek, ArXiv q-NC (2009). date_created: 2018-12-11T12:04:52Z date_published: 2009-01-01T00:00:00Z date_updated: 2021-01-12T07:51:48Z day: '01' extern: 1 main_file_link: - open_access: '1' url: http://arxiv.org/abs/0912.5409v1 month: '01' oa: 1 publication: ArXiv publication_status: published publisher: ArXiv publist_id: '2496' quality_controlled: 0 status: public title: Spin glass models for a network of real neurons type: preprint volume: q-bio.NC year: '2009' ...