---
_id: '3648'
abstract:
- lang: eng
text: 'We investigate the probability of fixation of a chromosome rearrangement
in a subdivided population, concentrating on the limit where migration is so large
relative to selection (m ≫ s) that the population can be thought of as being continuously
distributed. We study two demes, and one- and two-dimensional populations. For
two demes, the probability of fixation in the limit of high migration approximates
that of a population with twice the size of a single deme: migration therefore
greatly reduces the fixation probability. However, this behavior does not extend
to a large array of demes. Then, the fixation probability depends primarily on
neighborhood size (Nb), and may be appreciable even with strong selection and
free gene flow (≈exp(-B·Nb) in one dimension, ≈exp(-B\cdotNb) in two dimensions).
Our results are close to those for the more tractable case of a polygenic character
under disruptive selection.'
author:
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Shahin
full_name: Rouhani, Shahin
last_name: Rouhani
citation:
ama: Barton NH, Rouhani S. The probability of fixation of a new karyotype in a continuous
population. *Evolution*. 1991;45(3):499-517.
apa: Barton, N. H., & Rouhani, S. (1991). The probability of fixation of a new
karyotype in a continuous population. *Evolution*, *45*(3), 499–517.
chicago: 'Barton, Nicholas H, and Shahin Rouhani. “The Probability of Fixation of
a New Karyotype in a Continuous Population.” *Evolution* 45, no. 3 (1991):
499–517.'
ieee: N. H. Barton and S. Rouhani, “The probability of fixation of a new karyotype
in a continuous population,” *Evolution*, vol. 45, no. 3, pp. 499–517, 1991.
ista: Barton NH, Rouhani S. 1991. The probability of fixation of a new karyotype
in a continuous population. Evolution. 45(3), 499–517.
mla: Barton, Nicholas H., and Shahin Rouhani. “The Probability of Fixation of a
New Karyotype in a Continuous Population.” *Evolution*, vol. 45, no. 3, Wiley-Blackwell,
1991, pp. 499–517.
short: N.H. Barton, S. Rouhani, Evolution 45 (1991) 499–517.
date_created: 2018-12-11T12:04:25Z
date_published: 1991-05-01T00:00:00Z
date_updated: 2019-04-26T07:22:32Z
day: '01'
extern: 1
intvolume: ' 45'
issue: '3'
main_file_link:
- open_access: '0'
url: http://www.jstor.org/stable/2409908
month: '05'
page: 499 - 517
publication: Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2735'
quality_controlled: 0
status: public
title: The probability of fixation of a new karyotype in a continuous population
type: journal_article
volume: 45
year: '1991'
...