[{"publication":"Evolution","abstract":[{"text":"We investigate the probability of fixation of a chromosome rearrangement in a subdivided population, concentrating on the limit where migration is so large relative to selection (m ≫ s) that the population can be thought of as being continuously distributed. We study two demes, and one- and two-dimensional populations. For two demes, the probability of fixation in the limit of high migration approximates that of a population with twice the size of a single deme: migration therefore greatly reduces the fixation probability. However, this behavior does not extend to a large array of demes. Then, the fixation probability depends primarily on neighborhood size (Nb), and may be appreciable even with strong selection and free gene flow (≈exp(-B·Nb) in one dimension, ≈exp(-B\\cdotNb) in two dimensions). Our results are close to those for the more tractable case of a polygenic character under disruptive selection.","lang":"eng"}],"quality_controlled":0,"date_updated":"2019-04-26T07:22:32Z","intvolume":" 45","publication_status":"published","issue":"3","year":"1991","main_file_link":[{"open_access":"0","url":"http://www.jstor.org/stable/2409908"}],"type":"journal_article","publist_id":"2735","citation":{"short":"N.H. Barton, S. Rouhani, Evolution 45 (1991) 499–517.","mla":"Barton, Nicholas H., and Shahin Rouhani. “The Probability of Fixation of a New Karyotype in a Continuous Population.” *Evolution*, vol. 45, no. 3, Wiley-Blackwell, 1991, pp. 499–517.","ista":"Barton NH, Rouhani S. 1991. The probability of fixation of a new karyotype in a continuous population. Evolution. 45(3), 499–517.","ama":"Barton NH, Rouhani S. The probability of fixation of a new karyotype in a continuous population. *Evolution*. 1991;45(3):499-517.","apa":"Barton, N. H., & Rouhani, S. (1991). The probability of fixation of a new karyotype in a continuous population. *Evolution*, *45*(3), 499–517.","chicago":"Barton, Nicholas H, and Shahin Rouhani. “The Probability of Fixation of a New Karyotype in a Continuous Population.” *Evolution* 45, no. 3 (1991): 499–517.","ieee":"N. H. Barton and S. Rouhani, “The probability of fixation of a new karyotype in a continuous population,” *Evolution*, vol. 45, no. 3, pp. 499–517, 1991."},"title":"The probability of fixation of a new karyotype in a continuous population","month":"05","date_published":"1991-05-01T00:00:00Z","_id":"3648","publisher":"Wiley-Blackwell","volume":45,"status":"public","date_created":"2018-12-11T12:04:25Z","author":[{"orcid":"0000-0002-8548-5240","first_name":"Nicholas H","last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Nicholas Barton"},{"full_name":"Rouhani, Shahin","first_name":"Shahin","last_name":"Rouhani"}],"page":"499 - 517","day":"01","extern":1}]