@misc{3595, abstract = {Genome sizes vary enormously. This variation in DNA content correlates with effective population size, suggesting that deleterious additions to the genome can accumulate in small populations. On this view, the increased complexity of biological functions associated with large genomes partly reflects evolutionary degeneration.}, author = {Charlesworth, Brian and Nicholas Barton}, booktitle = {Current Biology}, number = {6}, pages = {R233 -- R235}, publisher = {Cell Press}, title = {{Genome size: Does bigger mean worse?}}, doi = {10.1016/j.cub.2004.02.054}, volume = {14}, year = {2004}, }