--- _id: '3537' abstract: - lang: eng text: 'Hippocampal place cells that fire together within the same cycle of theta oscillations represent the sequence of positions (movement trajectory) that a rat traverses on a linear track. Furthermore, it has been suggested that the encoding of these and other types of temporal memory sequences is organized by gamma oscillations nested within theta oscillations. Here, we examined whether gamma-related firing of place cells permits such discrete temporal coding. We found that gamma-modulated CA1 pyramidal cells separated into two classes on the basis of gamma firing phases during waking theta periods. These groups also differed in terms of their spike waveforms, firing rates, and burst firing tendency. During gamma oscillations one group''s firing became restricted to theta phases associated with the highest gamma power. Consequently, on the linear track, cells in this group often failed to fire early in theta-phase precession (as the rat entered the place field) if gamma oscillations were present. The second group fired throughout the theta cycle during gamma oscillations, and maintained gamma-modulated firing at different stages of theta-phase precession. Our results suggest that the two different pyramidal cell classes may support different types of population codes within a theta cycle: one in which spike sequences representing movement trajectories occur across subsequent gamma cycles nested within each theta cycle, and another in which firing in synchronized gamma discharges without temporal sequences encode a representation of location. We propose that gamma oscillations during theta-phase precession organize the mnemonic recall of population patterns representing places and movement paths.' author: - first_name: Timothy full_name: Senior,Timothy J last_name: Senior - first_name: John full_name: Huxter,John R last_name: Huxter - first_name: Kevin full_name: Allen, Kevin last_name: Allen - first_name: Joseph full_name: Joseph O'Neill id: 426376DC-F248-11E8-B48F-1D18A9856A87 last_name: O'Neill - first_name: Jozsef L full_name: Jozsef Csicsvari id: 3FA14672-F248-11E8-B48F-1D18A9856A87 last_name: Csicsvari orcid: 0000-0002-5193-4036 citation: ama: Senior T, Huxter J, Allen K, O’Neill J, Csicsvari JL. Gamma oscillatory firing reveals distinct populations of pyramidal cells in the CA1 region of the hippocampus. Journal of Neuroscience. 2008;28(9):2274-2286. doi:10.1523/JNEUROSCI.4669-07.2008 apa: Senior, T., Huxter, J., Allen, K., O’Neill, J., & Csicsvari, J. L. (2008). Gamma oscillatory firing reveals distinct populations of pyramidal cells in the CA1 region of the hippocampus. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.4669-07.2008 chicago: Senior, Timothy, John Huxter, Kevin Allen, Joseph O’Neill, and Jozsef L Csicsvari. “Gamma Oscillatory Firing Reveals Distinct Populations of Pyramidal Cells in the CA1 Region of the Hippocampus.” Journal of Neuroscience. Society for Neuroscience, 2008. https://doi.org/10.1523/JNEUROSCI.4669-07.2008. ieee: T. Senior, J. Huxter, K. Allen, J. O’Neill, and J. L. Csicsvari, “Gamma oscillatory firing reveals distinct populations of pyramidal cells in the CA1 region of the hippocampus,” Journal of Neuroscience, vol. 28, no. 9. Society for Neuroscience, pp. 2274–2286, 2008. ista: Senior T, Huxter J, Allen K, O’Neill J, Csicsvari JL. 2008. Gamma oscillatory firing reveals distinct populations of pyramidal cells in the CA1 region of the hippocampus. Journal of Neuroscience. 28(9), 2274–2286. mla: Senior, Timothy, et al. “Gamma Oscillatory Firing Reveals Distinct Populations of Pyramidal Cells in the CA1 Region of the Hippocampus.” Journal of Neuroscience, vol. 28, no. 9, Society for Neuroscience, 2008, pp. 2274–86, doi:10.1523/JNEUROSCI.4669-07.2008. short: T. Senior, J. Huxter, K. Allen, J. O’Neill, J.L. Csicsvari, Journal of Neuroscience 28 (2008) 2274–2286. date_created: 2018-12-11T12:03:51Z date_published: 2008-02-27T00:00:00Z date_updated: 2021-01-12T07:44:09Z day: '27' doi: 10.1523/JNEUROSCI.4669-07.2008 extern: 1 intvolume: ' 28' issue: '9' month: '02' page: 2274 - 2286 publication: Journal of Neuroscience publication_status: published publisher: Society for Neuroscience publist_id: '2847' quality_controlled: 0 status: public title: Gamma oscillatory firing reveals distinct populations of pyramidal cells in the CA1 region of the hippocampus type: journal_article volume: 28 year: '2008' ...