{"citation":{"mla":"Burnashev, Nail, et al. “Calcium-Permeable AMPA-Kainate Receptors in Fusiform Cerebellar Glial Cells.” <i>Science</i>, vol. 256, no. 5063, American Association for the Advancement of Science, 1992, pp. 1566–70, doi:<a href=\"https://doi.org/10.1126/science.1317970\">10.1126/science.1317970</a>.","short":"N. Burnashev, A. Khodorova, P.M. Jonas, P. Helm, W. Wisden, H. Monyer, P. Seeburg, B. Sakmann, Science 256 (1992) 1566–1570.","ieee":"N. Burnashev <i>et al.</i>, “Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells.,” <i>Science</i>, vol. 256, no. 5063. American Association for the Advancement of Science, pp. 1566–1570, 1992.","ista":"Burnashev N, Khodorova A, Jonas PM, Helm P, Wisden W, Monyer H, Seeburg P, Sakmann B. 1992. Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells. Science. 256(5063), 1566–1570.","chicago":"Burnashev, Nail, Alla Khodorova, Peter M Jonas, P. Helm, William Wisden, Hannah Monyer, Peter Seeburg, and Bert Sakmann. “Calcium-Permeable AMPA-Kainate Receptors in Fusiform Cerebellar Glial Cells.” <i>Science</i>. American Association for the Advancement of Science, 1992. <a href=\"https://doi.org/10.1126/science.1317970\">https://doi.org/10.1126/science.1317970</a>.","apa":"Burnashev, N., Khodorova, A., Jonas, P. M., Helm, P., Wisden, W., Monyer, H., … Sakmann, B. (1992). Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1317970\">https://doi.org/10.1126/science.1317970</a>","ama":"Burnashev N, Khodorova A, Jonas PM, et al. Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells. <i>Science</i>. 1992;256(5063):1566-1570. doi:<a href=\"https://doi.org/10.1126/science.1317970\">10.1126/science.1317970</a>"},"abstract":[{"lang":"eng","text":"Glutamate-operated ion channels (GluR channels) of the L-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-kainate subtype are found in both neurons and glial cells of the central nervous system. These channels are assembled from the GluR-A, -B, -C, and -D subunits; channels containing a GluR-B subunit show an outwardly rectifying current-voltage relation and low calcium permeability, whereas channels lacking the GluR-B subunit are characterized by a doubly rectifying current-voltage relation and high calcium permeability. Most cell types in the central nervous system coexpress several subunits, including GluR-B. However, Bergmann glia in rat cerebellum do not express GluR-B subunit genes. In a subset of cultured cerebellar glial cells, likely derived from Bergmann glial cells. GluR channels exhibit doubly rectifying current-voltage relations and high calcium permeability, whereas GluR channels of cerebellar neurons have low calcium permeability. Thus, differential expression of the GluR-B subunit gene in neurons and glia is one mechanism by which functional properties of native GluR channels are regulated."}],"author":[{"last_name":"Burnashev","full_name":"Burnashev, Nail","first_name":"Nail"},{"full_name":"Khodorova, Alla","last_name":"Khodorova","first_name":"Alla"},{"last_name":"Jonas","orcid":"0000-0001-5001-4804","full_name":"Jonas, Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M"},{"last_name":"Helm","full_name":"Helm, P.","first_name":"P."},{"first_name":"William","last_name":"Wisden","full_name":"Wisden, William"},{"first_name":"Hannah","full_name":"Monyer, Hannah","last_name":"Monyer"},{"first_name":"Peter","full_name":"Seeburg, Peter","last_name":"Seeburg"},{"last_name":"Sakmann","full_name":"Sakmann, Bert","first_name":"Bert"}],"title":"Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells.","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","language":[{"iso":"eng"}],"issue":"5063","article_type":"original","main_file_link":[{"url":"https://www.science.org/doi/10.1126/science.1317970"}],"publication_status":"published","pmid":1,"status":"public","publication":"Science","volume":256,"external_id":{"pmid":["1317970"]},"date_published":"1992-06-12T00:00:00Z","doi":"10.1126/science.1317970","article_processing_charge":"No","date_created":"2018-12-11T12:03:30Z","publist_id":"2918","month":"06","intvolume":"       256","extern":"1","publication_identifier":{"issn":["0036-8075"]},"year":"1992","page":"1566 - 1570","quality_controlled":"1","oa_version":"None","date_updated":"2022-03-16T13:24:52Z","scopus_import":"1","type":"journal_article","day":"12","_id":"3469","publisher":"American Association for the Advancement of Science"}