Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS
P.M. Jonas, N. Spruston, Current Opinion in Neurobiology 4 (1994) 366–372.
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Journal Article
| Published
Author
Jonas, Peter MIST Austria
;
Spruston, Nelson

Abstract
Excitatory postsynaptic currents in neurones of the central nervous system have a dual-component time course that results from the co-activation of AMPA/kainate-type and NMDA-type glutamate receptors. New approaches in electrophysiology and molecular biology have provided a better understanding of the factors that determine the kinectics of excitatory postsynaptic currents. Recent studies suggest that the time course of neurotransmitter concentration in the synaptic cleft, the gating properties of the native channels, and the glutamate receptor subunit composition all appear to be important factors.
Publishing Year
Date Published
1994-06-01
Journal Title
Current Opinion in Neurobiology
Volume
4
Issue
3
Page
366 - 372
IST-REx-ID
Cite this
Jonas PM, Spruston N. Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. Current Opinion in Neurobiology. 1994;4(3):366-372. doi:10.1016/0959-4388(94)90098-1
Jonas, P. M., & Spruston, N. (1994). Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. Current Opinion in Neurobiology. Elsevier. https://doi.org/10.1016/0959-4388(94)90098-1
Jonas, Peter M, and Nelson Spruston. “Mechanisms Shaping Glutamate-Mediated Excitatory Postsynaptic Currents in the CNS.” Current Opinion in Neurobiology. Elsevier, 1994. https://doi.org/10.1016/0959-4388(94)90098-1.
P. M. Jonas and N. Spruston, “Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS,” Current Opinion in Neurobiology, vol. 4, no. 3. Elsevier, pp. 366–372, 1994.
Jonas PM, Spruston N. 1994. Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. Current Opinion in Neurobiology. 4(3), 366–372.
Jonas, Peter M., and Nelson Spruston. “Mechanisms Shaping Glutamate-Mediated Excitatory Postsynaptic Currents in the CNS.” Current Opinion in Neurobiology, vol. 4, no. 3, Elsevier, 1994, pp. 366–72, doi:10.1016/0959-4388(94)90098-1.