{"volume":143,"abstract":[{"lang":"eng","text":"Auxin is a multifunctional hormone essential for plant development and pattern formation. A nuclear auxin-signaling system controlling auxin-induced gene expression is well established, but cytoplasmic auxin signaling, as in its coordination of cell polarization, is unexplored. We found a cytoplasmic auxin-signaling mechanism that modulates the interdigitated growth of Arabidopsis leaf epidermal pavement cells (PCs), which develop interdigitated lobes and indentations to form a puzzle-piece shape in a two-dimensional plane. PC interdigitation is compromised in leaves deficient in either auxin biosynthesis or its export mediated by PINFORMED 1 localized at the lobe tip. Auxin coordinately activates two Rho GTPases, ROP2 and ROP6, which promote the formation of complementary lobes and indentations, respectively. Activation of these ROPs by auxin occurs within 30 s and depends on AUXIN-BINDING PROTEIN 1. These findings reveal Rho GTPase-based auxin-signaling mechanisms, which modulate the spatial coordination of cell expansion across a field of cells."}],"date_updated":"2021-01-12T07:40:53Z","publist_id":"3625","author":[{"full_name":"Xu, Tongda","last_name":"Xu","first_name":"Tongda"},{"full_name":"Wen, Mingzhang","first_name":"Mingzhang","last_name":"Wen"},{"last_name":"Nagawa","first_name":"Shingo","full_name":"Nagawa, Shingo"},{"last_name":"Fu","first_name":"Ying","full_name":"Fu, Ying"},{"first_name":"Jin","last_name":"Chen","full_name":"Chen, Jin-Gui"},{"last_name":"Wu","first_name":"Ming","full_name":"Wu, Ming-Jing"},{"first_name":"Catherine","last_name":"Perrot Rechenmann","full_name":"Perrot-Rechenmann, Catherine"},{"first_name":"Jirí","orcid":"0000-0002-8302-7596","last_name":"Friml","full_name":"Jirí Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Jones, Alan M","first_name":"Alan","last_name":"Jones"},{"last_name":"Yang","first_name":"Zhenbiao","full_name":"Yang, Zhenbiao"}],"status":"public","date_created":"2018-12-11T12:01:14Z","publication":"Cell","publication_status":"published","issue":"1","doi":"10.1016/j.cell.2010.09.003","type":"journal_article","page":"99 - 110","_id":"3076","extern":1,"date_published":"2010-10-01T00:00:00Z","citation":{"chicago":"Xu, Tongda, Mingzhang Wen, Shingo Nagawa, Ying Fu, Jin Chen, Ming Wu, Catherine Perrot Rechenmann, Jiří Friml, Alan Jones, and Zhenbiao Yang. “Cell Surface- and Rho GTPase-Based Auxin Signaling Controls Cellular Interdigitation in Arabidopsis.” <i>Cell</i>. Cell Press, 2010. <a href=\"https://doi.org/10.1016/j.cell.2010.09.003\">https://doi.org/10.1016/j.cell.2010.09.003</a>.","ista":"Xu T, Wen M, Nagawa S, Fu Y, Chen J, Wu M, Perrot Rechenmann C, Friml J, Jones A, Yang Z. 2010. Cell surface- and Rho GTPase-based auxin signaling controls cellular interdigitation in Arabidopsis. Cell. 143(1), 99–110.","apa":"Xu, T., Wen, M., Nagawa, S., Fu, Y., Chen, J., Wu, M., … Yang, Z. (2010). Cell surface- and Rho GTPase-based auxin signaling controls cellular interdigitation in Arabidopsis. <i>Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cell.2010.09.003\">https://doi.org/10.1016/j.cell.2010.09.003</a>","mla":"Xu, Tongda, et al. “Cell Surface- and Rho GTPase-Based Auxin Signaling Controls Cellular Interdigitation in Arabidopsis.” <i>Cell</i>, vol. 143, no. 1, Cell Press, 2010, pp. 99–110, doi:<a href=\"https://doi.org/10.1016/j.cell.2010.09.003\">10.1016/j.cell.2010.09.003</a>.","short":"T. Xu, M. Wen, S. Nagawa, Y. Fu, J. Chen, M. Wu, C. Perrot Rechenmann, J. Friml, A. Jones, Z. Yang, Cell 143 (2010) 99–110.","ama":"Xu T, Wen M, Nagawa S, et al. Cell surface- and Rho GTPase-based auxin signaling controls cellular interdigitation in Arabidopsis. <i>Cell</i>. 2010;143(1):99-110. doi:<a href=\"https://doi.org/10.1016/j.cell.2010.09.003\">10.1016/j.cell.2010.09.003</a>","ieee":"T. Xu <i>et al.</i>, “Cell surface- and Rho GTPase-based auxin signaling controls cellular interdigitation in Arabidopsis,” <i>Cell</i>, vol. 143, no. 1. Cell Press, pp. 99–110, 2010."},"intvolume":"       143","title":"Cell surface- and Rho GTPase-based auxin signaling controls cellular interdigitation in Arabidopsis","quality_controlled":0,"publisher":"Cell Press","day":"01","year":"2010","month":"10"}