---
_id: '3044'
abstract:
- lang: eng
text: 'The signalling molecule auxin controls plant morphogenesis via its activity
gradients, which are produced by intercellular auxin transport. Cellular auxin
efflux is the rate-limiting step in this process and depends on PIN and phosphoglycoprotein
(PGP) auxin transporters. Mutual roles for these proteins in auxin transport are
unclear, as is the significance of their interactions for plant development. Here,
we have analysed the importance of the functional interaction between PIN- and
PGP-dependent auxin transport in development. We show by analysis of inducible
overexpression lines that PINs and PGPs define distinct auxin transport mechanisms:
both mediate auxin efflux but they play diverse developmental roles. Components
of both systems are expressed during embryogenesis, organogenesis and tropisms,
and they interact genetically in both synergistic and antagonistic fashions. A
concerted action of PIN- and PGP-dependent efflux systems is required for asymmetric
auxin distribution during these processes. We propose a model in which PGP-mediated
efflux controls auxin levels in auxin channel-forming cells and, thus, auxin availability
for PIN-dependent vectorial auxin movement.'
author:
- first_name: Jozef
full_name: Mravec, Jozef
last_name: Mravec
- first_name: Martin
full_name: Kubeš, Martin
last_name: Kubeš
- first_name: Agnieszka
full_name: Bielach, Agnieszka
last_name: Bielach
- first_name: Vassilena
full_name: Gaykova, Vassilena
last_name: Gaykova
- first_name: Jan
full_name: Petrášek, Jan
last_name: Petrášek
- first_name: Petr
full_name: Skůpa, Petr
last_name: Skůpa
- first_name: Suresh
full_name: Chand, Suresh
last_name: Chand
- first_name: Eva
full_name: Eva Benková
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Eva
full_name: Zažímalová, Eva
last_name: Zažímalová
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Mravec J, Kubeš M, Bielach A, et al. Interaction of PIN and PGP transport mechanisms
in auxin distribution-dependent development. Development. 2008;135(20):3345-3354.
doi:10.1242/dev.021071
apa: Mravec, J., Kubeš, M., Bielach, A., Gaykova, V., Petrášek, J., Skůpa, P., …
Friml, J. (2008). Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent
development. Development. Company of Biologists. https://doi.org/10.1242/dev.021071
chicago: Mravec, Jozef, Martin Kubeš, Agnieszka Bielach, Vassilena Gaykova, Jan
Petrášek, Petr Skůpa, Suresh Chand, Eva Benková, Eva Zažímalová, and Jiří Friml.
“Interaction of PIN and PGP Transport Mechanisms in Auxin Distribution-Dependent
Development.” Development. Company of Biologists, 2008. https://doi.org/10.1242/dev.021071.
ieee: J. Mravec et al., “Interaction of PIN and PGP transport mechanisms
in auxin distribution-dependent development,” Development, vol. 135, no.
20. Company of Biologists, pp. 3345–3354, 2008.
ista: Mravec J, Kubeš M, Bielach A, Gaykova V, Petrášek J, Skůpa P, Chand S, Benková
E, Zažímalová E, Friml J. 2008. Interaction of PIN and PGP transport mechanisms
in auxin distribution-dependent development. Development. 135(20), 3345–3354.
mla: Mravec, Jozef, et al. “Interaction of PIN and PGP Transport Mechanisms in Auxin
Distribution-Dependent Development.” Development, vol. 135, no. 20, Company
of Biologists, 2008, pp. 3345–54, doi:10.1242/dev.021071.
short: J. Mravec, M. Kubeš, A. Bielach, V. Gaykova, J. Petrášek, P. Skůpa, S. Chand,
E. Benková, E. Zažímalová, J. Friml, Development 135 (2008) 3345–3354.
date_created: 2018-12-11T12:01:02Z
date_published: 2008-10-15T00:00:00Z
date_updated: 2021-01-12T07:40:39Z
day: '15'
doi: 10.1242/dev.021071
extern: 1
intvolume: ' 135'
issue: '20'
month: '10'
page: 3345 - 3354
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '3658'
quality_controlled: 0
status: public
title: Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent
development
type: journal_article
volume: 135
year: '2008'
...