---
_id: '2867'
abstract:
- lang: eng
text: The plant hormone auxin elicits many specific context-dependent developmental
responses. Auxin promotes degradation of Aux/IAA proteins that prevent transcription
factors of the auxin response factor (ARF) family from regulating auxin-responsive
target genes. Aux/IAAs and ARFs are represented by large gene families in Arabidopsis.
Here we show that stabilization of BDL/IAA12 or its sister protein IAA13 prevents
MP/ARF5-dependent embryonic root formation whereas stabilized SHY2/IAA3 interferes
with seedling growth. Although both bdl and shy2-2 proteins inhibited MP/ARF5-dependent
reporter gene activation, shy2-2 was much less efficient than bdl to interfere
with embryonic root initiation when expressed from the BDL promoter. Similarly,
MP was much more efficient than ARF16 in this process. When expressed from the
SHY2 promoter, both shy2-2 and bdl inhibited cell elongation and auxin-induced
gene expression in the seedling hypocotyl. By contrast, gravitropism and auxin-induced
gene expression in the root, which were promoted by functionally redundant NPH4/ARF7
and ARF19 proteins, were inhibited by shy2-2, but not by bdl protein. Our results
suggest that auxin signals are converted into specific responses by matching pairs
of coexpressed ARF and Aux/IAA proteins.
author:
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
- first_name: Eva
full_name: Eva Benková
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Katja
full_name: Jäger, Katja E
last_name: Jäger
- first_name: Alexandra
full_name: Schlereth, Alexandra
last_name: Schlereth
- first_name: Thorsten
full_name: Hamann, Thorsten
last_name: Hamann
- first_name: Marika
full_name: Kientz, Marika
last_name: Kientz
- first_name: Jill
full_name: Wilmoth, Jill C
last_name: Wilmoth
- first_name: Jason
full_name: Reed, Jason W
last_name: Reed
- first_name: Gerd
full_name: Jürgens, Gerd
last_name: Jürgens
citation:
ama: Weijers D, Benková E, Jäger K, et al. Developmental specificity of auxin response
by pairs of ARF and Aux/IAA transcriptional regulators. EMBO Journal. 2005;24(10):1874-1885.
doi:10.1038/sj.emboj.7600659
apa: Weijers, D., Benková, E., Jäger, K., Schlereth, A., Hamann, T., Kientz, M.,
… Jürgens, G. (2005). Developmental specificity of auxin response by pairs of
ARF and Aux/IAA transcriptional regulators. EMBO Journal. Wiley-Blackwell.
https://doi.org/10.1038/sj.emboj.7600659
chicago: Weijers, Dolf, Eva Benková, Katja Jäger, Alexandra Schlereth, Thorsten
Hamann, Marika Kientz, Jill Wilmoth, Jason Reed, and Gerd Jürgens. “Developmental
Specificity of Auxin Response by Pairs of ARF and Aux/IAA Transcriptional Regulators.”
EMBO Journal. Wiley-Blackwell, 2005. https://doi.org/10.1038/sj.emboj.7600659.
ieee: D. Weijers et al., “Developmental specificity of auxin response by
pairs of ARF and Aux/IAA transcriptional regulators,” EMBO Journal, vol.
24, no. 10. Wiley-Blackwell, pp. 1874–1885, 2005.
ista: Weijers D, Benková E, Jäger K, Schlereth A, Hamann T, Kientz M, Wilmoth J,
Reed J, Jürgens G. 2005. Developmental specificity of auxin response by pairs
of ARF and Aux/IAA transcriptional regulators. EMBO Journal. 24(10), 1874–1885.
mla: Weijers, Dolf, et al. “Developmental Specificity of Auxin Response by Pairs
of ARF and Aux/IAA Transcriptional Regulators.” EMBO Journal, vol. 24,
no. 10, Wiley-Blackwell, 2005, pp. 1874–85, doi:10.1038/sj.emboj.7600659.
short: D. Weijers, E. Benková, K. Jäger, A. Schlereth, T. Hamann, M. Kientz, J.
Wilmoth, J. Reed, G. Jürgens, EMBO Journal 24 (2005) 1874–1885.
date_created: 2018-12-11T12:00:01Z
date_published: 2005-05-18T00:00:00Z
date_updated: 2021-01-12T07:00:22Z
day: '18'
doi: 10.1038/sj.emboj.7600659
extern: 1
intvolume: ' 24'
issue: '10'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142592/
month: '05'
oa: 1
page: 1874 - 1885
publication: EMBO Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3918'
quality_controlled: 0
status: public
title: Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional
regulators
type: journal_article
volume: 24
year: '2005'
...