Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators

D. Weijers, E. Benková, K. Jäger, A. Schlereth, T. Hamann, M. Kientz, J. Wilmoth, J. Reed, G. Jürgens, EMBO Journal 24 (2005) 1874–1885.


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Abstract
The plant hormone auxin elicits many specific context-dependent developmental responses. Auxin promotes degradation of Aux/IAA proteins that prevent transcription factors of the auxin response factor (ARF) family from regulating auxin-responsive target genes. Aux/IAAs and ARFs are represented by large gene families in Arabidopsis. Here we show that stabilization of BDL/IAA12 or its sister protein IAA13 prevents MP/ARF5-dependent embryonic root formation whereas stabilized SHY2/IAA3 interferes with seedling growth. Although both bdl and shy2-2 proteins inhibited MP/ARF5-dependent reporter gene activation, shy2-2 was much less efficient than bdl to interfere with embryonic root initiation when expressed from the BDL promoter. Similarly, MP was much more efficient than ARF16 in this process. When expressed from the SHY2 promoter, both shy2-2 and bdl inhibited cell elongation and auxin-induced gene expression in the seedling hypocotyl. By contrast, gravitropism and auxin-induced gene expression in the root, which were promoted by functionally redundant NPH4/ARF7 and ARF19 proteins, were inhibited by shy2-2, but not by bdl protein. Our results suggest that auxin signals are converted into specific responses by matching pairs of coexpressed ARF and Aux/IAA proteins.
Publishing Year
Date Published
2005-05-18
Journal Title
EMBO Journal
Volume
24
Issue
10
Page
1874 - 1885
IST-REx-ID

Cite this

Weijers D, Benková E, Jäger K, et al. Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators. EMBO Journal. 2005;24(10):1874-1885. doi:10.1038/sj.emboj.7600659
Weijers, D., Benková, E., Jäger, K., Schlereth, A., Hamann, T., Kientz, M., … Jürgens, G. (2005). Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators. EMBO Journal, 24(10), 1874–1885. https://doi.org/10.1038/sj.emboj.7600659
Weijers, Dolf, Eva Benková, Katja Jäger, Alexandra Schlereth, Thorsten Hamann, Marika Kientz, Jill Wilmoth, Jason Reed, and Gerd Jürgens. “Developmental Specificity of Auxin Response by Pairs of ARF and Aux/IAA Transcriptional Regulators.” EMBO Journal 24, no. 10 (2005): 1874–85. https://doi.org/10.1038/sj.emboj.7600659.
D. Weijers et al., “Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators,” EMBO Journal, vol. 24, no. 10, pp. 1874–1885, 2005.
Weijers D, Benková E, Jäger K, Schlereth A, Hamann T, Kientz M, Wilmoth J, Reed J, Jürgens G. 2005. Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators. EMBO Journal. 24(10), 1874–1885.
Weijers, Dolf, et al. “Developmental Specificity of Auxin Response by Pairs of ARF and Aux/IAA Transcriptional Regulators.” EMBO Journal, vol. 24, no. 10, Wiley-Blackwell, 2005, pp. 1874–85, doi:10.1038/sj.emboj.7600659.

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