{"publication":"Neuroscience Letters","issue":"3","publication_status":"published","doi":"10.1016/j.neulet.2005.06.068","page":"144 - 148","type":"journal_article","_id":"2656","date_updated":"2021-01-12T06:58:51Z","publist_id":"4241","abstract":[{"text":"Previous studies have shown that neurons in the sacral dorsal commissural nucleus (SDCN) express neurokinin-1 receptor (NK1R) and can be modulated by the co-release of GABA and glycine (Gly) from single presynaptic terminal. These results raise the possibility that GABA/Gly-cocontaining terminals might make synaptic contacts with NK1R-expressing neurons in the SDCN. In order to provide morphological evidence for this hypothesis, the triple-immunohistochemical studies were performed in the SDCN. Triple-immunofluorescence histochemical study showed that some axon terminals in close association with NK1R-immunopositive (NK1R-ip) neurons in the SDCN were immunopositive for both glutamic acid decarboxylase (GAD) and glycine transporter 2 (GlyT2). In electron microscopic dual- and triple-immunohistochemistry for GAD/GlyT2, GAD/NK1R, GlyT2/NK1R, or GAD/GlyT2/NK1R also revealed dually labeled (GAD/GlyT2-ip) synaptic terminals upon SDCN neurons, as well as GAD- and/or GlyT2-ip axon terminals in synaptic contact with NK1R-ip SDCN neurons. These results suggested that some synaptic terminals upon NK1R-expressing SDCN neurons co-released both GABA and Gly.","lang":"eng"}],"volume":388,"author":[{"last_name":"Feng","first_name":"Yu","full_name":"Feng, Yu-Peng"},{"full_name":"Li, Yun-Qing","first_name":"Yun","last_name":"Li"},{"full_name":"Wang, Wen","last_name":"Wang","first_name":"Wen"},{"full_name":"Wu, Sheng-Xi","first_name":"Sheng","last_name":"Wu"},{"last_name":"Chen","first_name":"Tao","full_name":"Chen, Tao"},{"first_name":"Ryuichi","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Mizuno, Noboru","first_name":"Noboru","last_name":"Mizuno"}],"date_created":"2018-12-11T11:58:54Z","status":"public","publisher":"Elsevier","day":"18","year":"2005","month":"11","citation":{"mla":"Feng, Yu, et al. “Morphological Evidence for GABA/Glycine-Cocontaining Terminals in Synaptic Contact with Neurokinin-1 Receptor-Expressing Neurons in the Sacral Dorsal Commissural Nucleus of the Rat.” <i>Neuroscience Letters</i>, vol. 388, no. 3, Elsevier, 2005, pp. 144–48, doi:<a href=\"https://doi.org/10.1016/j.neulet.2005.06.068\">10.1016/j.neulet.2005.06.068</a>.","short":"Y. Feng, Y. Li, W. Wang, S. Wu, T. Chen, R. Shigemoto, N. Mizuno, Neuroscience Letters 388 (2005) 144–148.","ieee":"Y. Feng <i>et al.</i>, “Morphological evidence for GABA/glycine-cocontaining terminals in synaptic contact with neurokinin-1 receptor-expressing neurons in the sacral dorsal commissural nucleus of the rat,” <i>Neuroscience Letters</i>, vol. 388, no. 3. Elsevier, pp. 144–148, 2005.","ama":"Feng Y, Li Y, Wang W, et al. Morphological evidence for GABA/glycine-cocontaining terminals in synaptic contact with neurokinin-1 receptor-expressing neurons in the sacral dorsal commissural nucleus of the rat. <i>Neuroscience Letters</i>. 2005;388(3):144-148. doi:<a href=\"https://doi.org/10.1016/j.neulet.2005.06.068\">10.1016/j.neulet.2005.06.068</a>","chicago":"Feng, Yu, Yun Li, Wen Wang, Sheng Wu, Tao Chen, Ryuichi Shigemoto, and Noboru Mizuno. “Morphological Evidence for GABA/Glycine-Cocontaining Terminals in Synaptic Contact with Neurokinin-1 Receptor-Expressing Neurons in the Sacral Dorsal Commissural Nucleus of the Rat.” <i>Neuroscience Letters</i>. Elsevier, 2005. <a href=\"https://doi.org/10.1016/j.neulet.2005.06.068\">https://doi.org/10.1016/j.neulet.2005.06.068</a>.","apa":"Feng, Y., Li, Y., Wang, W., Wu, S., Chen, T., Shigemoto, R., &#38; Mizuno, N. (2005). Morphological evidence for GABA/glycine-cocontaining terminals in synaptic contact with neurokinin-1 receptor-expressing neurons in the sacral dorsal commissural nucleus of the rat. <i>Neuroscience Letters</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neulet.2005.06.068\">https://doi.org/10.1016/j.neulet.2005.06.068</a>","ista":"Feng Y, Li Y, Wang W, Wu S, Chen T, Shigemoto R, Mizuno N. 2005. Morphological evidence for GABA/glycine-cocontaining terminals in synaptic contact with neurokinin-1 receptor-expressing neurons in the sacral dorsal commissural nucleus of the rat. Neuroscience Letters. 388(3), 144–148."},"extern":1,"date_published":"2005-11-18T00:00:00Z","intvolume":"       388","title":"Morphological evidence for GABA/glycine-cocontaining terminals in synaptic contact with neurokinin-1 receptor-expressing neurons in the sacral dorsal commissural nucleus of the rat","quality_controlled":0}