---
_id: '2562'
abstract:
- lang: eng
text: A monoclonal antibody against a metabotropic glutamate receptor, mGluR2, was
produced by using a glutathione S-transferase (GST) fusion protein containing
an N-terminal sequence of rat mGluR2. Intense mGluR2-like immunoreactivity (mGluR2-LI)
was seen mainly in neuropil of the cerebral cortical regions, hippocampus, olfactory
bulb, some diencephalic nuclei, dorsal cochlear nucleus and cerebellar cortex.
In the cerebellar cortex, mGluR2-LI was seen only in Golgi cells. In Ammon's hem,
mGluR2-LI was marked in the stratum lucidum of CA3 and the stratum lacunosum-moleculare
of CA1-CA3, but not detected in the stratum pyramidale. The results indicate that
mGluR2 is located not only presynaptically but also postsynaptically.
acknowledgement: We are grateful to Mr. Akira Uesugi for photographic help.
article_processing_charge: No
article_type: original
author:
- first_name: Akio
full_name: Neki, Akio
last_name: Neki
- first_name: Hitoshi
full_name: Ohishi, Hitoshi
last_name: Ohishi
- first_name: Takeshi
full_name: Kaneko, Takeshi
last_name: Kaneko
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
- first_name: Noboru
full_name: Mizuno, Noboru
last_name: Mizuno
citation:
ama: 'Neki A, Ohishi H, Kaneko T, Shigemoto R, Nakanishi S, Mizuno N. Pre- and postsynaptic
localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An
immunohistochemical study with a monoclonal antibody. Neuroscience Letters.
1996;202(3):197-200. doi:10.1016/0304-3940(95)12248-6'
apa: 'Neki, A., Ohishi, H., Kaneko, T., Shigemoto, R., Nakanishi, S., & Mizuno,
N. (1996). Pre- and postsynaptic localization of a metabotropic glutamate receptor,
mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody.
Neuroscience Letters. Elsevier. https://doi.org/10.1016/0304-3940(95)12248-6'
chicago: 'Neki, Akio, Hitoshi Ohishi, Takeshi Kaneko, Ryuichi Shigemoto, Shigetada
Nakanishi, and Noboru Mizuno. “Pre- and Postsynaptic Localization of a Metabotropic
Glutamate Receptor, MGluR2, in the Rat Brain: An Immunohistochemical Study with
a Monoclonal Antibody.” Neuroscience Letters. Elsevier, 1996. https://doi.org/10.1016/0304-3940(95)12248-6.'
ieee: 'A. Neki, H. Ohishi, T. Kaneko, R. Shigemoto, S. Nakanishi, and N. Mizuno,
“Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2,
in the rat brain: An immunohistochemical study with a monoclonal antibody,” Neuroscience
Letters, vol. 202, no. 3. Elsevier, pp. 197–200, 1996.'
ista: 'Neki A, Ohishi H, Kaneko T, Shigemoto R, Nakanishi S, Mizuno N. 1996. Pre-
and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in
the rat brain: An immunohistochemical study with a monoclonal antibody. Neuroscience
Letters. 202(3), 197–200.'
mla: 'Neki, Akio, et al. “Pre- and Postsynaptic Localization of a Metabotropic Glutamate
Receptor, MGluR2, in the Rat Brain: An Immunohistochemical Study with a Monoclonal
Antibody.” Neuroscience Letters, vol. 202, no. 3, Elsevier, 1996, pp. 197–200,
doi:10.1016/0304-3940(95)12248-6.'
short: A. Neki, H. Ohishi, T. Kaneko, R. Shigemoto, S. Nakanishi, N. Mizuno, Neuroscience
Letters 202 (1996) 197–200.
date_created: 2018-12-11T11:58:24Z
date_published: 1996-01-05T00:00:00Z
date_updated: 2022-08-12T12:04:18Z
day: '05'
doi: 10.1016/0304-3940(95)12248-6
extern: '1'
external_id:
pmid:
- '8848265'
intvolume: ' 202'
issue: '3'
language:
- iso: eng
month: '01'
oa_version: None
page: 197 - 200
pmid: 1
publication: Neuroscience Letters
publication_identifier:
issn:
- 0304-3940
publication_status: published
publisher: Elsevier
publist_id: '4335'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2,
in the rat brain: An immunohistochemical study with a monoclonal antibody'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 202
year: '1996'
...