--- _id: '2558' abstract: - lang: eng text: Brain areas involved in the genesis and control of daily rhythms receive a prominent neural input that contains the neurotransmitter substance P (SP), a peptide putatively involved in the synchronization of circadian rhythms by environmental light. We investigated the localization of receptors to SP in the suprachiasmatic nucleus of the hypothalamus (SCN) and in the intergeniculate leaflet of the thalamus (IGL) of the rat and hamster using in situ hybridization histochemistry and immunohistochemistry. Consistently with that previously described in the rat, a neuronal population distributed along the lateral margin and at the dorso-latero-caudal aspect of the hamster SCN expresses moderately the mRNA encoding the SP receptor. In both rat and hamster, immunohistochemical data confirm the previous finding and reveal an almost complete absence of SP receptors in the ventral part of the SCN, which receives a direct projection from the retina. In the IGL of both species, numerous neurons prominently express the mRNA encoding the SP receptor. The immunostaining shows a high density of SP receptors on perikarya and dendrites throughout the nucleus. A dense staining is also observed on individual cells and processes bordering the lumen of blood vessels in the SCN and IGL. article_processing_charge: No article_type: original author: - first_name: Gérard full_name: Mick, Gérard last_name: Mick - first_name: Ryuichi full_name: Shigemoto, Ryuichi id: 499F3ABC-F248-11E8-B48F-1D18A9856A87 last_name: Shigemoto orcid: 0000-0001-8761-9444 - first_name: Kunio full_name: Kitahama, Kunio last_name: Kitahama citation: ama: Mick G, Shigemoto R, Kitahama K. Localization of substance P receptors in central neural structures controlling daily rhythms in nocturnal rodents. Comptes Rendus de l’Academie des Sciences - Series III. 1995;318(2):209-217. apa: Mick, G., Shigemoto, R., & Kitahama, K. (1995). Localization of substance P receptors in central neural structures controlling daily rhythms in nocturnal rodents. Comptes Rendus de l’Academie Des Sciences - Series III. Gauthier Villars Editeur. chicago: Mick, Gérard, Ryuichi Shigemoto, and Kunio Kitahama. “Localization of Substance P Receptors in Central Neural Structures Controlling Daily Rhythms in Nocturnal Rodents.” Comptes Rendus de l’Academie Des Sciences - Series III. Gauthier Villars Editeur, 1995. ieee: G. Mick, R. Shigemoto, and K. Kitahama, “Localization of substance P receptors in central neural structures controlling daily rhythms in nocturnal rodents,” Comptes Rendus de l’Academie des Sciences - Series III, vol. 318, no. 2. Gauthier Villars Editeur, pp. 209–217, 1995. ista: Mick G, Shigemoto R, Kitahama K. 1995. Localization of substance P receptors in central neural structures controlling daily rhythms in nocturnal rodents. Comptes Rendus de l’Academie des Sciences - Series III. 318(2), 209–217. mla: Mick, Gérard, et al. “Localization of Substance P Receptors in Central Neural Structures Controlling Daily Rhythms in Nocturnal Rodents.” Comptes Rendus de l’Academie Des Sciences - Series III, vol. 318, no. 2, Gauthier Villars Editeur, 1995, pp. 209–17. short: G. Mick, R. Shigemoto, K. Kitahama, Comptes Rendus de l’Academie Des Sciences - Series III 318 (1995) 209–217. date_created: 2018-12-11T11:58:23Z date_published: 1995-02-01T00:00:00Z date_updated: 2022-06-29T08:18:48Z day: '01' extern: '1' external_id: pmid: - '7757814 ' intvolume: ' 318' issue: '2' language: - iso: eng main_file_link: - url: https://pubmed.ncbi.nlm.nih.gov/7757814/ month: '02' oa_version: None page: 209 - 217 pmid: 1 publication: Comptes Rendus de l'Academie des Sciences - Series III publication_identifier: issn: - 0764-4469 publication_status: published publisher: Gauthier Villars Editeur publist_id: '4340' quality_controlled: '1' scopus_import: '1' status: public title: Localization of substance P receptors in central neural structures controlling daily rhythms in nocturnal rodents type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 318 year: '1995' ...