--- _id: '2071' abstract: - lang: eng text: The X or Z chromosome has several characteristics that distinguish it from the autosomes, namely hemizygosity in the heterogametic sex, and a potentially different effective population size, both of which may influence the rate and nature of evolution. In particular, there may be an accelerated rate of adaptive change for X-linked compared to autosomal coding sequences, often referred to as the Faster-X effect. Empirical studies have indicated that the strength of Faster-X evolution varies among different species, and theoretical treatments have shown that demography and mating system can substantially affect the degree of Faster-X evolution. Here we integrate genomic data on Faster-X evolution from a variety of animals with the demographic factors, mating system, and sex chromosome regulatory characteristics that may influence it. Our results suggest that differences in effective population size and mechanisms of dosage compensation may influence the perceived extent of Faster-X evolution, and help to explain several clade-specific patterns that we observe. acknowledgement: We gratefully acknowledge funding from the Royal Society (to JEM) author: - first_name: Judith full_name: Mank, Judith E last_name: Mank - first_name: Beatriz full_name: Beatriz Vicoso id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87 last_name: Vicoso orcid: 0000-0002-4579-8306 - first_name: Sofia full_name: Berlin, Sofia last_name: Berlin - first_name: Brian full_name: Charlesworth, Brian last_name: Charlesworth citation: ama: 'Mank J, Vicoso B, Berlin S, Charlesworth B. Effective population size and the Faster-X effect: Empirical results and their interpretation. Evolution. 2010;64(3):663-674. doi:10.1111/j.1558-5646.2009.00853.x' apa: 'Mank, J., Vicoso, B., Berlin, S., & Charlesworth, B. (2010). Effective population size and the Faster-X effect: Empirical results and their interpretation. Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.2009.00853.x' chicago: 'Mank, Judith, Beatriz Vicoso, Sofia Berlin, and Brian Charlesworth. “Effective Population Size and the Faster-X Effect: Empirical Results and Their Interpretation.” Evolution. Wiley-Blackwell, 2010. https://doi.org/10.1111/j.1558-5646.2009.00853.x.' ieee: 'J. Mank, B. Vicoso, S. Berlin, and B. Charlesworth, “Effective population size and the Faster-X effect: Empirical results and their interpretation,” Evolution, vol. 64, no. 3. Wiley-Blackwell, pp. 663–674, 2010.' ista: 'Mank J, Vicoso B, Berlin S, Charlesworth B. 2010. Effective population size and the Faster-X effect: Empirical results and their interpretation. Evolution. 64(3), 663–674.' mla: 'Mank, Judith, et al. “Effective Population Size and the Faster-X Effect: Empirical Results and Their Interpretation.” Evolution, vol. 64, no. 3, Wiley-Blackwell, 2010, pp. 663–74, doi:10.1111/j.1558-5646.2009.00853.x.' short: J. Mank, B. Vicoso, S. Berlin, B. Charlesworth, Evolution 64 (2010) 663–674. date_created: 2018-12-11T11:55:32Z date_published: 2010-03-01T00:00:00Z date_updated: 2021-01-12T06:55:07Z day: '01' doi: 10.1111/j.1558-5646.2009.00853.x extern: 1 intvolume: ' 64' issue: '3' month: '03' page: 663 - 674 publication: Evolution publication_status: published publisher: Wiley-Blackwell publist_id: '4967' quality_controlled: 0 status: public title: 'Effective population size and the Faster-X effect: Empirical results and their interpretation' type: journal_article volume: 64 year: '2010' ...