---
_id: '2071'
abstract:
- lang: eng
text: The X or Z chromosome has several characteristics that distinguish it from
the autosomes, namely hemizygosity in the heterogametic sex, and a potentially
different effective population size, both of which may influence the rate and
nature of evolution. In particular, there may be an accelerated rate of adaptive
change for X-linked compared to autosomal coding sequences, often referred to
as the Faster-X effect. Empirical studies have indicated that the strength of
Faster-X evolution varies among different species, and theoretical treatments
have shown that demography and mating system can substantially affect the degree
of Faster-X evolution. Here we integrate genomic data on Faster-X evolution from
a variety of animals with the demographic factors, mating system, and sex chromosome
regulatory characteristics that may influence it. Our results suggest that differences
in effective population size and mechanisms of dosage compensation may influence
the perceived extent of Faster-X evolution, and help to explain several clade-specific
patterns that we observe.
acknowledgement: We gratefully acknowledge funding from the Royal Society (to JEM)
author:
- first_name: Judith
full_name: Mank, Judith E
last_name: Mank
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Sofia
full_name: Berlin, Sofia
last_name: Berlin
- first_name: Brian
full_name: Charlesworth, Brian
last_name: Charlesworth
citation:
ama: 'Mank J, Vicoso B, Berlin S, Charlesworth B. Effective population size and
the Faster-X effect: Empirical results and their interpretation. Evolution.
2010;64(3):663-674. doi:10.1111/j.1558-5646.2009.00853.x'
apa: 'Mank, J., Vicoso, B., Berlin, S., & Charlesworth, B. (2010). Effective
population size and the Faster-X effect: Empirical results and their interpretation.
Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.2009.00853.x'
chicago: 'Mank, Judith, Beatriz Vicoso, Sofia Berlin, and Brian Charlesworth. “Effective
Population Size and the Faster-X Effect: Empirical Results and Their Interpretation.”
Evolution. Wiley-Blackwell, 2010. https://doi.org/10.1111/j.1558-5646.2009.00853.x.'
ieee: 'J. Mank, B. Vicoso, S. Berlin, and B. Charlesworth, “Effective population
size and the Faster-X effect: Empirical results and their interpretation,” Evolution,
vol. 64, no. 3. Wiley-Blackwell, pp. 663–674, 2010.'
ista: 'Mank J, Vicoso B, Berlin S, Charlesworth B. 2010. Effective population size
and the Faster-X effect: Empirical results and their interpretation. Evolution.
64(3), 663–674.'
mla: 'Mank, Judith, et al. “Effective Population Size and the Faster-X Effect: Empirical
Results and Their Interpretation.” Evolution, vol. 64, no. 3, Wiley-Blackwell,
2010, pp. 663–74, doi:10.1111/j.1558-5646.2009.00853.x.'
short: J. Mank, B. Vicoso, S. Berlin, B. Charlesworth, Evolution 64 (2010) 663–674.
date_created: 2018-12-11T11:55:32Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T06:55:07Z
day: '01'
doi: 10.1111/j.1558-5646.2009.00853.x
extern: 1
intvolume: ' 64'
issue: '3'
month: '03'
page: 663 - 674
publication: Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4967'
quality_controlled: 0
status: public
title: 'Effective population size and the Faster-X effect: Empirical results and their
interpretation'
type: journal_article
volume: 64
year: '2010'
...