--- _id: '1917' abstract: - lang: eng text: Auxin-binding protein 1 (ABP1) was discovered nearly 40 years ago and was shown to be essential for plant development and morphogenesis, but its mode of action remains unclear. Here, we report that the plasma membrane-localized transmembrane kinase (TMK) receptor-like kinases interact with ABP1 and transduce auxin signal to activate plasma membrane-associated ROPs [Rho-like guanosine triphosphatases (GTPase) from plants], leading to changes in the cytoskeleton and the shape of leaf pavement cells in Arabidopsis. The interaction between ABP1 and TMK at the cell surface is induced by auxin and requires ABP1 sensing of auxin. These findings show that TMK proteins and ABP1 form a cell surface auxin perception complex that activates ROP signaling pathways, regulating nontranscriptional cytoplasmic responses and associated fundamental processes. acknowledgement: Supported by the intramural research program of the National Institute of Arthritis and Musculoskeletal and Skin Diseases and by its Laboratory Animal Care and Use Section and Flow Cytometry Group, Office of Science and Technology article_processing_charge: No article_type: original author: - first_name: Tongda full_name: Xu, Tongda last_name: Xu - first_name: Ning full_name: Dai, Ning last_name: Dai - first_name: Jisheng full_name: Chen, Jisheng last_name: Chen - first_name: Shingo full_name: Nagawa, Shingo last_name: Nagawa - first_name: Min full_name: Cao, Min last_name: Cao - first_name: Hongjiang full_name: Li, Hongjiang id: 33CA54A6-F248-11E8-B48F-1D18A9856A87 last_name: Li orcid: 0000-0001-5039-9660 - first_name: Zimin full_name: Zhou, Zimin last_name: Zhou - first_name: Xu full_name: Chen, Xu id: 4E5ADCAA-F248-11E8-B48F-1D18A9856A87 last_name: Chen - first_name: Riet full_name: De Rycke, Riet last_name: De Rycke - first_name: Hana full_name: Rakusová, Hana last_name: Rakusová - first_name: Wen full_name: Wang, Wen last_name: Wang - first_name: Alan full_name: Jones, Alan last_name: Jones - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Sara full_name: Patterson, Sara last_name: Patterson - first_name: Anthony full_name: Bleecker, Anthony last_name: Bleecker - first_name: Zhenbiao full_name: Yang, Zhenbiao last_name: Yang citation: ama: Xu T, Dai N, Chen J, et al. Cell surface ABP1-TMK auxin sensing complex activates ROP GTPase signaling. Science. 2014;343(6174):1025-1028. doi:10.1126/science.1245125 apa: Xu, T., Dai, N., Chen, J., Nagawa, S., Cao, M., Li, H., … Yang, Z. (2014). Cell surface ABP1-TMK auxin sensing complex activates ROP GTPase signaling. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1245125 chicago: Xu, Tongda, Ning Dai, Jisheng Chen, Shingo Nagawa, Min Cao, Hongjiang Li, Zimin Zhou, et al. “Cell Surface ABP1-TMK Auxin Sensing Complex Activates ROP GTPase Signaling.” Science. American Association for the Advancement of Science, 2014. https://doi.org/10.1126/science.1245125. ieee: T. Xu et al., “Cell surface ABP1-TMK auxin sensing complex activates ROP GTPase signaling,” Science, vol. 343, no. 6174. American Association for the Advancement of Science, pp. 1025–1028, 2014. ista: Xu T, Dai N, Chen J, Nagawa S, Cao M, Li H, Zhou Z, Chen X, De Rycke R, Rakusová H, Wang W, Jones A, Friml J, Patterson S, Bleecker A, Yang Z. 2014. Cell surface ABP1-TMK auxin sensing complex activates ROP GTPase signaling. Science. 343(6174), 1025–1028. mla: Xu, Tongda, et al. “Cell Surface ABP1-TMK Auxin Sensing Complex Activates ROP GTPase Signaling.” Science, vol. 343, no. 6174, American Association for the Advancement of Science, 2014, pp. 1025–28, doi:10.1126/science.1245125. short: T. Xu, N. Dai, J. Chen, S. Nagawa, M. Cao, H. Li, Z. Zhou, X. Chen, R. De Rycke, H. Rakusová, W. Wang, A. Jones, J. Friml, S. Patterson, A. Bleecker, Z. Yang, Science 343 (2014) 1025–1028. date_created: 2018-12-11T11:54:42Z date_published: 2014-02-28T00:00:00Z date_updated: 2021-01-12T06:54:03Z day: '28' department: - _id: JiFr doi: 10.1126/science.1245125 external_id: pmid: - '24578577' intvolume: ' 343' issue: '6174' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166562/ month: '02' oa: 1 oa_version: Submitted Version page: 1025 - 1028 pmid: 1 publication: Science publication_status: published publisher: American Association for the Advancement of Science publist_id: '5177' quality_controlled: '1' scopus_import: 1 status: public title: Cell surface ABP1-TMK auxin sensing complex activates ROP GTPase signaling type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 343 year: '2014' ...