Excitement about inhibitory presynaptic terminals

D.H. Vandael, C.M. Espinoza Martinez, P.M. Jonas, Neuron 85 (2015) 1149–1151.

Download
OA 411.83 KB
OA IST-2017-822-v1+2_Perspective_Final2.pdf 100.77 KB

Journal Article | Published | English
Department
Abstract
Based on extrapolation from excitatory synapses, it is often assumed that depletion of the releasable pool of synaptic vesicles is the main factor underlying depression at inhibitory synapses. In this issue of Neuron, using subcellular patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba (2015) show that at Purkinje cell-deep cerebellar nuclei neuron synapses, changes in presynaptic action potential waveform substantially contribute to synaptic depression. Based on extrapolation from excitatory synapses, it is often assumed that depletion of the releasable pool of synaptic vesicles is the main factor underlying depression at inhibitory synapses. In this issue of Neuron, using subcellular patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba (2015) show that at Purkinje cell-deep cerebellar nuclei neuron synapses, changes in presynaptic action potential waveform substantially contribute to synaptic depression.
Publishing Year
Date Published
2015-03-18
Journal Title
Neuron
Volume
85
Issue
6
Page
1149 - 1151
IST-REx-ID

Cite this

Vandael DH, Espinoza Martinez CM, Jonas PM. Excitement about inhibitory presynaptic terminals. Neuron. 2015;85(6):1149-1151. doi:10.1016/j.neuron.2015.03.006
Vandael, D. H., Espinoza Martinez, C. M., & Jonas, P. M. (2015). Excitement about inhibitory presynaptic terminals. Neuron, 85(6), 1149–1151. https://doi.org/10.1016/j.neuron.2015.03.006
Vandael, David H, Claudia M Espinoza Martinez, and Peter M Jonas. “Excitement about Inhibitory Presynaptic Terminals.” Neuron 85, no. 6 (2015): 1149–51. https://doi.org/10.1016/j.neuron.2015.03.006.
D. H. Vandael, C. M. Espinoza Martinez, and P. M. Jonas, “Excitement about inhibitory presynaptic terminals,” Neuron, vol. 85, no. 6, pp. 1149–1151, 2015.
Vandael DH, Espinoza Martinez CM, Jonas PM. 2015. Excitement about inhibitory presynaptic terminals. Neuron. 85(6), 1149–1151.
Vandael, David H., et al. “Excitement about Inhibitory Presynaptic Terminals.” Neuron, vol. 85, no. 6, Elsevier, 2015, pp. 1149–51, doi:10.1016/j.neuron.2015.03.006.
All files available under the following license(s):
Creative Commons License:
Creative Commons Attribution-NonCommercial (CC BY-NC 4.0)
Main File(s)
Access Level
OA Open Access
Last Uploaded
2018-12-12T10:16:07Z
Access Level
OA Open Access
Last Uploaded
2018-12-12T10:16:07Z


Export

Marked Publications

Open Data IST Research Explorer

Search this title in

Google Scholar