---
_id: '1717'
abstract:
- lang: eng
text: 'Two key processes are in the basis of morphogenesis: the spatial allocation
of cell types in fields of naïve cells and the regulation of growth. Both are
controlled by morphogens, which activate target genes in the growing tissue in
a concentration-dependent manner. Thus the morphogen model is an intrinsically
quantitative concept. However, quantitative studies were performed only in recent
years on two morphogens: Bicoid and Decapentaplegic. This review covers quantitative
aspects of the formation and precision of the Decapentaplegic morphogen gradient.
The morphogen gradient concept is transitioning from a soft definition to a precise
idea of what the gradient could really do.'
acknowledgement: This work was supported by the University of Geneva, Max Planck Society,
VW, EU, SNF, and HFSP
author:
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Marcos
full_name: González-Gaitán, Marcos A
last_name: González Gaitán
citation:
ama: Kicheva A, González Gaitán M. The Decapentaplegic morphogen gradient a precise
definition. Current Opinion in Cell Biology. 2008;20(2):137-143. doi:10.1016/j.ceb.2008.01.008
apa: Kicheva, A., & González Gaitán, M. (2008). The Decapentaplegic morphogen
gradient a precise definition. Current Opinion in Cell Biology. Elsevier.
https://doi.org/10.1016/j.ceb.2008.01.008
chicago: Kicheva, Anna, and Marcos González Gaitán. “The Decapentaplegic Morphogen
Gradient a Precise Definition.” Current Opinion in Cell Biology. Elsevier,
2008. https://doi.org/10.1016/j.ceb.2008.01.008.
ieee: A. Kicheva and M. González Gaitán, “The Decapentaplegic morphogen gradient
a precise definition,” Current Opinion in Cell Biology, vol. 20, no. 2.
Elsevier, pp. 137–143, 2008.
ista: Kicheva A, González Gaitán M. 2008. The Decapentaplegic morphogen gradient
a precise definition. Current Opinion in Cell Biology. 20(2), 137–143.
mla: Kicheva, Anna, and Marcos González Gaitán. “The Decapentaplegic Morphogen Gradient
a Precise Definition.” Current Opinion in Cell Biology, vol. 20, no. 2,
Elsevier, 2008, pp. 137–43, doi:10.1016/j.ceb.2008.01.008.
short: A. Kicheva, M. González Gaitán, Current Opinion in Cell Biology 20 (2008)
137–143.
date_created: 2018-12-11T11:53:38Z
date_published: 2008-04-01T00:00:00Z
date_updated: 2021-01-12T06:52:44Z
day: '01'
doi: 10.1016/j.ceb.2008.01.008
extern: 1
intvolume: ' 20'
issue: '2'
month: '04'
page: 137 - 143
publication: Current Opinion in Cell Biology
publication_status: published
publisher: Elsevier
publist_id: '5412'
quality_controlled: 0
status: public
title: The Decapentaplegic morphogen gradient a precise definition
type: journal_article
volume: 20
year: '2008'
...