--- _id: '1717' abstract: - lang: eng text: 'Two key processes are in the basis of morphogenesis: the spatial allocation of cell types in fields of naïve cells and the regulation of growth. Both are controlled by morphogens, which activate target genes in the growing tissue in a concentration-dependent manner. Thus the morphogen model is an intrinsically quantitative concept. However, quantitative studies were performed only in recent years on two morphogens: Bicoid and Decapentaplegic. This review covers quantitative aspects of the formation and precision of the Decapentaplegic morphogen gradient. The morphogen gradient concept is transitioning from a soft definition to a precise idea of what the gradient could really do.' acknowledgement: This work was supported by the University of Geneva, Max Planck Society, VW, EU, SNF, and HFSP author: - first_name: Anna full_name: Anna Kicheva id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 - first_name: Marcos full_name: González-Gaitán, Marcos A last_name: González Gaitán citation: ama: Kicheva A, González Gaitán M. The Decapentaplegic morphogen gradient a precise definition. Current Opinion in Cell Biology. 2008;20(2):137-143. doi:10.1016/j.ceb.2008.01.008 apa: Kicheva, A., & González Gaitán, M. (2008). The Decapentaplegic morphogen gradient a precise definition. Current Opinion in Cell Biology. Elsevier. https://doi.org/10.1016/j.ceb.2008.01.008 chicago: Kicheva, Anna, and Marcos González Gaitán. “The Decapentaplegic Morphogen Gradient a Precise Definition.” Current Opinion in Cell Biology. Elsevier, 2008. https://doi.org/10.1016/j.ceb.2008.01.008. ieee: A. Kicheva and M. González Gaitán, “The Decapentaplegic morphogen gradient a precise definition,” Current Opinion in Cell Biology, vol. 20, no. 2. Elsevier, pp. 137–143, 2008. ista: Kicheva A, González Gaitán M. 2008. The Decapentaplegic morphogen gradient a precise definition. Current Opinion in Cell Biology. 20(2), 137–143. mla: Kicheva, Anna, and Marcos González Gaitán. “The Decapentaplegic Morphogen Gradient a Precise Definition.” Current Opinion in Cell Biology, vol. 20, no. 2, Elsevier, 2008, pp. 137–43, doi:10.1016/j.ceb.2008.01.008. short: A. Kicheva, M. González Gaitán, Current Opinion in Cell Biology 20 (2008) 137–143. date_created: 2018-12-11T11:53:38Z date_published: 2008-04-01T00:00:00Z date_updated: 2021-01-12T06:52:44Z day: '01' doi: 10.1016/j.ceb.2008.01.008 extern: 1 intvolume: ' 20' issue: '2' month: '04' page: 137 - 143 publication: Current Opinion in Cell Biology publication_status: published publisher: Elsevier publist_id: '5412' quality_controlled: 0 status: public title: The Decapentaplegic morphogen gradient a precise definition type: journal_article volume: 20 year: '2008' ...