--- _id: '11333' abstract: - lang: eng text: Adenosine triphosphate (ATP) is the energy source for various biochemical processes and biomolecular motors in living things. Development of ATP antagonists and their stimuli-controlled actions offer a novel approach to regulate biological processes. Herein, we developed azobenzene-based photoswitchable ATP antagonists for controlling the activity of motor proteins; cytoplasmic and axonemal dyneins. The new ATP antagonists showed reversible photoswitching of cytoplasmic dynein activity in an in vitro dynein-microtubule system due to the trans and cis photoisomerization of their azobenzene segment. Importantly, our ATP antagonists reversibly regulated the axonemal dynein motor activity for the force generation in a demembranated model of Chlamydomonas reinhardtii. We found that the trans and cis isomers of ATP antagonists significantly differ in their affinity to the ATP binding site. article_number: e202200807 article_processing_charge: No article_type: original author: - first_name: Sampreeth full_name: Thayyil, Sampreeth last_name: Thayyil - first_name: Yukinori full_name: Nishigami, Yukinori last_name: Nishigami - first_name: Muhammad J full_name: Islam, Muhammad J id: C94881D2-008F-11EA-8E08-2637E6697425 last_name: Islam - first_name: P. K. full_name: Hashim, P. K. last_name: Hashim - first_name: Ken'Ya full_name: Furuta, Ken'Ya last_name: Furuta - first_name: Kazuhiro full_name: Oiwa, Kazuhiro last_name: Oiwa - first_name: Jian full_name: Yu, Jian last_name: Yu - first_name: Min full_name: Yao, Min last_name: Yao - first_name: Toshiyuki full_name: Nakagaki, Toshiyuki last_name: Nakagaki - first_name: Nobuyuki full_name: Tamaoki, Nobuyuki last_name: Tamaoki citation: ama: Thayyil S, Nishigami Y, Islam MJ, et al. Dynamic control of microbial movement by photoswitchable ATP antagonists. Chemistry - A European Journal. 2022;28(30). doi:10.1002/chem.202200807 apa: Thayyil, S., Nishigami, Y., Islam, M. J., Hashim, P. K., Furuta, K., Oiwa, K., … Tamaoki, N. (2022). Dynamic control of microbial movement by photoswitchable ATP antagonists. Chemistry - A European Journal. Wiley. https://doi.org/10.1002/chem.202200807 chicago: Thayyil, Sampreeth, Yukinori Nishigami, Muhammad J Islam, P. K. Hashim, Ken’Ya Furuta, Kazuhiro Oiwa, Jian Yu, Min Yao, Toshiyuki Nakagaki, and Nobuyuki Tamaoki. “Dynamic Control of Microbial Movement by Photoswitchable ATP Antagonists.” Chemistry - A European Journal. Wiley, 2022. https://doi.org/10.1002/chem.202200807. ieee: S. Thayyil et al., “Dynamic control of microbial movement by photoswitchable ATP antagonists,” Chemistry - A European Journal, vol. 28, no. 30. Wiley, 2022. ista: Thayyil S, Nishigami Y, Islam MJ, Hashim PK, Furuta K, Oiwa K, Yu J, Yao M, Nakagaki T, Tamaoki N. 2022. Dynamic control of microbial movement by photoswitchable ATP antagonists. Chemistry - A European Journal. 28(30), e202200807. mla: Thayyil, Sampreeth, et al. “Dynamic Control of Microbial Movement by Photoswitchable ATP Antagonists.” Chemistry - A European Journal, vol. 28, no. 30, e202200807, Wiley, 2022, doi:10.1002/chem.202200807. short: S. Thayyil, Y. Nishigami, M.J. Islam, P.K. Hashim, K. Furuta, K. Oiwa, J. Yu, M. Yao, T. Nakagaki, N. Tamaoki, Chemistry - A European Journal 28 (2022). date_created: 2022-04-24T22:01:44Z date_published: 2022-05-25T00:00:00Z date_updated: 2023-10-03T10:58:31Z day: '25' department: - _id: RySh doi: 10.1002/chem.202200807 external_id: isi: - '000781658800001' pmid: - '35332959' intvolume: ' 28' isi: 1 issue: '30' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1002/chem.202200807 month: '05' oa: 1 oa_version: Published Version pmid: 1 publication: Chemistry - A European Journal publication_identifier: eissn: - '15213765' issn: - '09476539' publication_status: published publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: Dynamic control of microbial movement by photoswitchable ATP antagonists type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 28 year: '2022' ...