{"status":"public","abstract":[{"lang":"eng","text":"Cell geometry is tightly coupled to gene expression patterns within the tissue microenvironment. This perspective synthesizes evidence that the 3D organization of chromosomes is a critical intermediate for geometric control of genomic programs. Using a combination of experiments and modeling we outline approaches to decipher the mechano-genomic code that governs cellular homeostasis and reprogramming."}],"date_published":"2016-07-27T00:00:00Z","oa_version":"None","type":"journal_article","publist_id":"6289","publication_status":"published","extern":"1","volume":6,"publication":"BioArchitecture","month":"07","publisher":"Taylor & Francis","citation":{"ama":"Uhler C, Shivashankar GV. Geometric control and modeling of genome reprogramming. <i>BioArchitecture</i>. 2016;6(4):76-84. doi:<a href=\"https://doi.org/10.1080/19490992.2016.1201620\">10.1080/19490992.2016.1201620</a>","chicago":"Uhler, Caroline, and G V Shivashankar. “Geometric Control and Modeling of Genome Reprogramming.” <i>BioArchitecture</i>. Taylor &#38; Francis, 2016. <a href=\"https://doi.org/10.1080/19490992.2016.1201620\">https://doi.org/10.1080/19490992.2016.1201620</a>.","apa":"Uhler, C., &#38; Shivashankar, G. V. (2016). Geometric control and modeling of genome reprogramming. <i>BioArchitecture</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.1080/19490992.2016.1201620\">https://doi.org/10.1080/19490992.2016.1201620</a>","short":"C. Uhler, G.V. Shivashankar, BioArchitecture 6 (2016) 76–84.","ieee":"C. Uhler and G. V. Shivashankar, “Geometric control and modeling of genome reprogramming,” <i>BioArchitecture</i>, vol. 6, no. 4. Taylor &#38; Francis, pp. 76–84, 2016.","ista":"Uhler C, Shivashankar GV. 2016. Geometric control and modeling of genome reprogramming. BioArchitecture. 6(4), 76–84.","mla":"Uhler, Caroline, and G. V. Shivashankar. “Geometric Control and Modeling of Genome Reprogramming.” <i>BioArchitecture</i>, vol. 6, no. 4, Taylor &#38; Francis, 2016, pp. 76–84, doi:<a href=\"https://doi.org/10.1080/19490992.2016.1201620\">10.1080/19490992.2016.1201620</a>."},"page":"76 - 84","issue":"4","year":"2016","day":"27","_id":"1088","doi":"10.1080/19490992.2016.1201620","quality_controlled":"1","intvolume":"         6","author":[{"full_name":"Uhler, Caroline","last_name":"Uhler","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7008-0216","first_name":"Caroline"},{"full_name":"Shivashankar, G V","last_name":"Shivashankar","first_name":"G V"}],"date_created":"2018-12-11T11:50:05Z","language":[{"iso":"eng"}],"date_updated":"2021-01-12T06:48:11Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","title":"Geometric control and modeling of genome reprogramming"}