Rigidity transitions in development and disease

Hannezo EB, Heisenberg C-PJ. 2022. Rigidity transitions in development and disease. Trends in Cell Biology.

Download
No fulltext has been uploaded. References only!

Journal Article | Epub ahead of print | English

Scopus indexed
Abstract
Although rigidity and jamming transitions have been widely studied in physics and material science, their importance in a number of biological processes, including embryo development, tissue homeostasis, wound healing, and disease progression, has only begun to be recognized in the past few years. The hypothesis that biological systems can undergo rigidity/jamming transitions is attractive, as it would allow these systems to change their material properties rapidly and strongly. However, whether such transitions indeed occur in biological systems, how they are being regulated, and what their physiological relevance might be, is still being debated. Here, we review theoretical and experimental advances from the past few years, focusing on the regulation and role of potential tissue rigidity transitions in different biological processes.
Publishing Year
Date Published
2022-01-17
Journal Title
Trends in Cell Biology
Acknowledgement
We thank present and former members of the Heisenberg and Hannezo groups, in particular Bernat Corominas-Murtra and Nicoletta Petridou, for helpful discussions, and Claudia Flandoli for the artwork. We apologize for not being able to cite a number of highly relevant studies, to stay within the maximum allowed number of citations.
ISSN
eISSN
IST-REx-ID

Cite this

Hannezo EB, Heisenberg C-PJ. Rigidity transitions in development and disease. Trends in Cell Biology. 2022. doi:10.1016/j.tcb.2021.12.006
Hannezo, E. B., & Heisenberg, C.-P. J. (2022). Rigidity transitions in development and disease. Trends in Cell Biology. Cell Press ; Elsevier. https://doi.org/10.1016/j.tcb.2021.12.006
Hannezo, Edouard B, and Carl-Philipp J Heisenberg. “Rigidity Transitions in Development and Disease.” Trends in Cell Biology. Cell Press ; Elsevier, 2022. https://doi.org/10.1016/j.tcb.2021.12.006.
E. B. Hannezo and C.-P. J. Heisenberg, “Rigidity transitions in development and disease,” Trends in Cell Biology. Cell Press ; Elsevier, 2022.
Hannezo EB, Heisenberg C-PJ. 2022. Rigidity transitions in development and disease. Trends in Cell Biology.
Hannezo, Edouard B., and Carl-Philipp J. Heisenberg. “Rigidity Transitions in Development and Disease.” Trends in Cell Biology, Cell Press ; Elsevier, 2022, doi:10.1016/j.tcb.2021.12.006.

Export

Marked Publications

Open Data ISTA Research Explorer

Sources

PMID: 35058104
PubMed | Europe PMC

Search this title in

Google Scholar