{"citation":{"mla":"Nikonorova, N., et al. “The Arabidopsis Root Tip (Phospho)Proteomes at Growth-Promoting versus Growth-Repressing Conditions Reveal Novel Root Growth Regulators.” <i>Cells</i>, vol. 10, 1665, MDPI, 2021, doi:<a href=\"https://doi.org/10.3390/cells10071665\">10.3390/cells10071665</a>.","short":"N. Nikonorova, E. Murphy, C. Fonseca de Lima, S. Zhu, B. van de Cotte, L. Vu, D. Balcerowicz, L. Li, X. Kong, G. De Rop, T. Beeckman, J. Friml, K. Vissenberg, P. Morris, Z. Ding, I. De Smet, Cells 10 (2021).","ieee":"N. Nikonorova <i>et al.</i>, “The Arabidopsis root tip (phospho)proteomes at growth-promoting versus growth-repressing conditions reveal novel root growth regulators,” <i>Cells</i>, vol. 10. MDPI, 2021.","ama":"Nikonorova N, Murphy E, Fonseca de Lima C, et al. The Arabidopsis root tip (phospho)proteomes at growth-promoting versus growth-repressing conditions reveal novel root growth regulators. <i>Cells</i>. 2021;10. doi:<a href=\"https://doi.org/10.3390/cells10071665\">10.3390/cells10071665</a>","chicago":"Nikonorova, N, E Murphy, CF Fonseca de Lima, S Zhu, B van de Cotte, LD Vu, D Balcerowicz, et al. “The Arabidopsis Root Tip (Phospho)Proteomes at Growth-Promoting versus Growth-Repressing Conditions Reveal Novel Root Growth Regulators.” <i>Cells</i>. MDPI, 2021. <a href=\"https://doi.org/10.3390/cells10071665\">https://doi.org/10.3390/cells10071665</a>.","apa":"Nikonorova, N., Murphy, E., Fonseca de Lima, C., Zhu, S., van de Cotte, B., Vu, L., … De Smet, I. (2021). The Arabidopsis root tip (phospho)proteomes at growth-promoting versus growth-repressing conditions reveal novel root growth regulators. <i>Cells</i>. MDPI. <a href=\"https://doi.org/10.3390/cells10071665\">https://doi.org/10.3390/cells10071665</a>","ista":"Nikonorova N, Murphy E, Fonseca de Lima C, Zhu S, van de Cotte B, Vu L, Balcerowicz D, Li L, Kong X, De Rop G, Beeckman T, Friml J, Vissenberg K, Morris P, Ding Z, De Smet I. 2021. The Arabidopsis root tip (phospho)proteomes at growth-promoting versus growth-repressing conditions reveal novel root growth regulators. Cells. 10, 1665."},"date_published":"2021-07-02T00:00:00Z","intvolume":"        10","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"project":[{"grant_number":"665385","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"International IST Doctoral Program"},{"_id":"3AC91DDA-15DF-11EA-824D-93A3E7B544D1","call_identifier":"FWF","name":"FWF Open Access Fund"}],"keyword":["primary root","(phospho)proteomics","auxin","(receptor) kinase"],"title":"The Arabidopsis root tip (phospho)proteomes at growth-promoting versus growth-repressing conditions reveal novel root growth regulators","quality_controlled":"1","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"10083"}]},"publication_identifier":{"issn":["2073-4409"]},"year":"2021","month":"07","ec_funded":1,"date_updated":"2024-04-24T22:30:43Z","oa_version":"Published Version","alternative_title":["Protein Phosphorylation and Cell Signaling in Plants"],"author":[{"last_name":"Nikonorova","first_name":"N","full_name":"Nikonorova, N"},{"last_name":"Murphy","first_name":"E","full_name":"Murphy, E"},{"full_name":"Fonseca de Lima, CF","first_name":"CF","last_name":"Fonseca de Lima"},{"full_name":"Zhu, S","last_name":"Zhu","first_name":"S"},{"full_name":"van de Cotte, B","first_name":"B","last_name":"van de Cotte"},{"last_name":"Vu","first_name":"LD","full_name":"Vu, LD"},{"full_name":"Balcerowicz, D","first_name":"D","last_name":"Balcerowicz"},{"last_name":"Li","orcid":"0000-0002-5607-272X","first_name":"Lanxin","id":"367EF8FA-F248-11E8-B48F-1D18A9856A87","full_name":"Li, Lanxin"},{"first_name":"X","last_name":"Kong","full_name":"Kong, X"},{"full_name":"De Rop, G","first_name":"G","last_name":"De Rop"},{"full_name":"Beeckman, T","first_name":"T","last_name":"Beeckman"},{"orcid":"0000-0002-8302-7596","first_name":"Jiří","last_name":"Friml","full_name":"Friml, Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Vissenberg, K","last_name":"Vissenberg","first_name":"K"},{"full_name":"Morris, PC","first_name":"PC","last_name":"Morris"},{"last_name":"Ding","first_name":"Z","full_name":"Ding, Z"},{"first_name":"I","last_name":"De Smet","full_name":"De Smet, I"}],"external_id":{"pmid":["34359847"],"isi":["000676604700001"]},"status":"public","ddc":["575"],"article_number":"1665 ","acknowledgement":"We thank the Nottingham Stock Centre for seeds, Frank Van Breusegem for the phb3 mutant, and Herman Höfte for the the1 mutant. Open Access Funding by the Austrian Science Fund (FWF).","has_accepted_license":"1","article_type":"original","doi":"10.3390/cells10071665","type":"journal_article","file":[{"file_size":2667848,"relation":"main_file","content_type":"application/pdf","date_updated":"2021-09-16T09:07:06Z","success":1,"creator":"cchlebak","file_id":"10021","file_name":"2021_Cells_Nikonorova.pdf","access_level":"open_access","checksum":"2a9f534b9c2200e72e2cde95afaf4eed","date_created":"2021-09-16T09:07:06Z"}],"pmid":1,"department":[{"_id":"JiFr"}],"day":"02","publisher":"MDPI","article_processing_charge":"Yes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","isi":1,"file_date_updated":"2021-09-16T09:07:06Z","abstract":[{"text":"Auxin plays a dual role in growth regulation and, depending on the tissue and concentration of the hormone, it can either promote or inhibit division and expansion processes in plants. Recent studies have revealed that, beyond transcriptional reprogramming, alternative auxincontrolled mechanisms regulate root growth. Here, we explored the impact of different concentrations of the synthetic auxin NAA that establish growth-promoting and -repressing conditions on the root tip proteome and phosphoproteome, generating a unique resource. From the phosphoproteome data, we pinpointed (novel) growth regulators, such as the RALF34-THE1 module. Our results, together with previously published studies, suggest that auxin, H+-ATPases, cell wall modifications and cell wall sensing receptor-like kinases are tightly embedded in a pathway regulating cell elongation. Furthermore, our study assigned a novel role to MKK2 as a regulator of primary root growth and a (potential) regulator of auxin biosynthesis and signalling, and suggests the importance of the MKK2\r\nThr31 phosphorylation site for growth regulation in the Arabidopsis root tip.","lang":"eng"}],"volume":10,"date_created":"2021-09-14T11:36:20Z","language":[{"iso":"eng"}],"publication":"Cells","publication_status":"published","_id":"10015","oa":1}