Characterizing the fitness landscape on population and global scales

Project Period: 2019-01-01 – 2023-12-31
Externally Funded
Acronym
CharFL
Principal Investigator
Fyodor Kondrashov
Department(s)
Kondrashov Group
Grant Number
771209
Funding Organisation
EC/H2020

7 Publications

2019 | Journal Article | IST-REx-ID: 7181 | OA
Large multiple sequence alignments with a root-to-leaf regressive method
E. Garriga, P. Di Tommaso, C. Magis, I. Erb, L. Mansouri, A. Baltzis, H. Laayouni, F. Kondrashov, E. Floden, C. Notredame, Nature Biotechnology 37 (2019) 1466–1470.
View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
2022 | Journal Article | IST-REx-ID: 11187 | OA
Unlocking capacities of genomics for the COVID-19 response and future pandemics
Knyazev S, Chhugani K, Sarwal V, Ayyala R, Singh H, Karthikeyan S, Deshpande D, Baykal PI, Comarova Z, Lu A, Porozov Y, Vasylyeva TI, Wertheim JO, Tierney BT, Chiu CY, Sun R, Wu A, Abedalthagafi MS, Pak VM, Nagaraj SH, Smith AL, Skums P, Pasaniuc B, Komissarov A, Mason CE, Bortz E, Lemey P, Kondrashov F, Beerenwinkel N, Lam TTY, Wu NC, Zelikovsky A, Knight R, Crandall KA, Mangul S. 2022. Unlocking capacities of genomics for the COVID-19 response and future pandemics. Nature Methods. 19(4), 374–380.
View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
2021 | Journal Article | IST-REx-ID: 9905 | OA
Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains
S. Rella, Y.A. Kulikova, E.T. Dermitzakis, F. Kondrashov, Scientific Reports 11 (2021).
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2021 | Journal Article | IST-REx-ID: 9910 | OA
The limits of normal approximation for adult height
S.A. Slavskii, I.A. Kuznetsov, T.I. Shashkova, G.A. Bazykin, T.I. Axenovich, F. Kondrashov, Y.S. Aulchenko, European Journal of Human Genetics 29 (2021) 1082–1091.
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2022 | Journal Article | IST-REx-ID: 11448 | OA
Heterogeneity of the GFP fitness landscape and data-driven protein design
L. Gonzalez Somermeyer, A. Fleiss, A.S. Mishin, N.G. Bozhanova, A.A. Igolkina, J. Meiler, M.-E. Alaball Pujol, E.V. Putintseva, K.S. Sarkisyan, F. Kondrashov, ELife 11 (2022).
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2022 | Journal Article | IST-REx-ID: 11447 | OA
Relation between the number of peaks and the number of reciprocal sign epistatic interactions
R.J. Saona Urmeneta, F. Kondrashov, K. Khudiakova, Bulletin of Mathematical Biology 84 (2022).
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2020 | Journal Article | IST-REx-ID: 7889 | OA
Plants with genetically encoded autoluminescence
Mitiouchkina T, Mishin AS, Gonzalez Somermeyer L, Markina NM, Chepurnyh TV, Guglya EB, Karataeva TA, Palkina KA, Shakhova ES, Fakhranurova LI, Chekova SV, Tsarkova AS, Golubev YV, Negrebetsky VV, Dolgushin SA, Shalaev PV, Shlykov D, Melnik OA, Shipunova VO, Deyev SM, Bubyrev AI, Pushin AS, Choob VV, Dolgov SV, Kondrashov F, Yampolsky IV, Sarkisyan KS. 2020. Plants with genetically encoded autoluminescence. Nature Biotechnology. 38, 944–946.
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