Cellular navigation along spatial gradients

Project Period: 2017-04-01 – 2022-03-31
Externally Funded
Acronym
GradientSensing
Principal Investigator
Michael K Sixt
Department(s)
Sixt Group
Grant Number
724373
Funding Organisation
EC/H2020

7 Publications

2020 | Journal Article | IST-REx-ID: 7875 | OA
Microtubules control cellular shape and coherence in amoeboid migrating cells
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).
View | Files available | DOI | PubMed | Europe PMC
 
2020 | Journal Article | IST-REx-ID: 7885
Cellular locomotion using environmental topography
A. REVERSAT, F.R. Gärtner, J. Merrin, J.A. Stopp, S. Tasciyan, J.L. Aguilera Servin, I. de Vries, R. Hauschild, M. Hons, M. Piel, A. Callan-Jones, R. Voituriez, M.K. Sixt, Nature 582 (2020) 582–585.
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2020 | Journal Article | IST-REx-ID: 7909 | OA
Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
J. Damiano-Guercio, L. Kurzawa, J. Müller, G.A. Dimchev, M. Schaks, M. Nemethova, T. Pokrant, S. Brühmann, J. Linkner, L. Blanchoin, M.K. Sixt, K. Rottner, J. Faix, ELife 9 (2020).
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2018 | Journal Article | IST-REx-ID: 437 | OA
Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration
A.F. Leithner, J. Renkawitz, I. de Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
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2021 | Journal Article | IST-REx-ID: 9259 | OA
Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium
K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology 12 (2021).
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2019 | Journal Article | IST-REx-ID: 6328 | OA
Nuclear positioning facilitates amoeboid migration along the path of least resistance
J. Renkawitz, A. Kopf, J.A. Stopp, I. de Vries, M.K. Driscoll, J. Merrin, R. Hauschild, E.S. Welf, G. Danuser, R. Fiolka, M.K. Sixt, Nature 568 (2019) 546–550.
View | Files available | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
2018 | Journal Article | IST-REx-ID: 15 | OA
Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC