Microglia action towards neuronal circuit formation and function in health and disease
Project Period: 2017-05-01 – 2022-04-30
Externally Funded
Acronym
MICROGLIA-CIRCUIT
Principal Investigator
Sandra Siegert
Department(s)
Siegert Group
Grant Number
715571
Funding Organisation
EC/H2020
4 Publications
2021 | Journal Article | IST-REx-ID: 10565 | 
Minimally invasive protocols and quantification for microglia-mediated perineuronal net disassembly in mouse brain
A. Venturino, S. Siegert, STAR Protocols 2 (2021).
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| DOI
A. Venturino, S. Siegert, STAR Protocols 2 (2021).
2021 | Journal Article | IST-REx-ID: 10655 |
Optimizing AAV2/6 microglial targeting identified enhanced efficiency in the photoreceptor degenerative environment
M.E. Maes, G.M. Wögenstein, G. Colombo, R. Casado Polanco, S. Siegert, Molecular Therapy - Methods and Clinical Development 23 (2021) 210–224.
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M.E. Maes, G.M. Wögenstein, G. Colombo, R. Casado Polanco, S. Siegert, Molecular Therapy - Methods and Clinical Development 23 (2021) 210–224.
2019 | Journal Article | IST-REx-ID: 6521 |
Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges
M.E. Maes, G. Colombo, R. Schulz, S. Siegert, Neuroscience Letters 707 (2019).
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| PubMed | Europe PMC
M.E. Maes, G. Colombo, R. Schulz, S. Siegert, Neuroscience Letters 707 (2019).
2021 | Journal Article | IST-REx-ID: 9642 |
Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain
A. Venturino, R. Schulz, H. De Jesús-Cortés, M.E. Maes, B. Nagy, F. Reilly-Andújar, G. Colombo, R.J. Cubero, F.E. Schoot Uiterkamp, M.F. Bear, S. Siegert, Cell Reports 36 (2021).
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| Files available
| DOI
| PubMed | Europe PMC
A. Venturino, R. Schulz, H. De Jesús-Cortés, M.E. Maes, B. Nagy, F. Reilly-Andújar, G. Colombo, R.J. Cubero, F.E. Schoot Uiterkamp, M.F. Bear, S. Siegert, Cell Reports 36 (2021).