Limits to selection in biology and in evolutionary computation

Project Period: 2010-07-01 – 2015-06-30
Externally Funded
Acronym
SelectionInformation
Principal Investigator
Nicholas H Barton
Department(s)
Barton Group
Grant Number
250152
Funding Organisation
FP7_ERC

51 Publications

2017 | Journal Article | IST-REx-ID: 1199   OA
How does epistasis influence the response to selection?
N.H. Barton, Heredity 118 (2017) 96–109.
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2018 | Journal Article | IST-REx-ID: 316   OA
Evolutionary pathways for the generation of new self-incompatibility haplotypes in a non-self recognition system
K. Bodova, T. Priklopil, D. Field, N.H. Barton, M. Pickup, Genetics 209 (2018) 861–883.
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2017 | Journal Article | IST-REx-ID: 626   OA
The infinitesimal model: Definition derivation and implications
N.H. Barton, A. Etheridge, A. Véber, Theoretical Population Biology 118 (2017) 50–73.
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2017 | Journal Article | IST-REx-ID: 1074
Inferring recent demography from isolation by distance of long shared sequence blocks
H. Ringbauer, G. Coop, N.H. Barton, Genetics 205 (2017) 1335–1351.
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2017 | Journal Article | IST-REx-ID: 955
Evolution of new regulatory functions on biophysically realistic fitness landscapes
T. Friedlander, R. Prizak, N.H. Barton, G. Tkacik, Nature Communications 8 (2017).
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2016 | Journal Article | IST-REx-ID: 1358
Intrinsic limits to gene regulation by global crosstalk
T. Friedlander, R. Prizak, C.C. Guet, N.H. Barton, G. Tkacik, Nature Communications 7 (2016) 12307.
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2017 | Journal Article | IST-REx-ID: 1077   OA
Evolutionary interplay between structure, energy and epistasis in the coat protein of the fX174 phage family
R.A. Fernandes Redondo, H. Vladar, T. Włodarski, J.P. Bollback, Journal of the Royal Society Interface 14 (2017).
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2015 | Journal Article | IST-REx-ID: 1818   OA
Limits to adaptation along environmental gradients
J. Polechova, N.H. Barton, PNAS 112 (2015) 6401–6406.
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2017 | Journal Article | IST-REx-ID: 1351
Model checking the evolution of gene regulatory networks
M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, Acta Informatica 54 (2017) 765–787.
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2013 | Journal Article | IST-REx-ID: 2842   OA
Inference in two dimensions: Allele frequencies versus lengths of shared sequence blocks
N.H. Barton, A. Etheridge, J. Kelleher, A. Véber, Theoretical Population Biology 87 (2013) 105–119.
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2012 | Journal Article | IST-REx-ID: 3131   OA
Limits to the rate of adaptive substitution in sexual populations
D. Weissman, N.H. Barton, PLoS Genetics 8 (2012).
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2011 | Journal Article | IST-REx-ID: 3390   OA
The relation between reproductive value and genetic contribution
N.H. Barton, A. Etheridge, Genetics 188 (2011) 953–973.
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2015 | Journal Article | IST-REx-ID: 1666
Dynamics of transcription factor binding site evolution
M. Tugrul, T. Paixao, N.H. Barton, G. Tkacik, PLoS Genetics 11 (2015).
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2015 | Journal Article | IST-REx-ID: 1542   OA
Toward a unifying framework for evolutionary processes
T. Paixao, G. Badkobeh, N.H. Barton, D. Çörüş, D. Dang, T. Friedrich, P. Lehre, D. Sudholt, A. Sutton, B. Trubenova, Journal of Theoretical Biology 383 (2015) 28–43.
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2016 | Journal Article | IST-REx-ID: 1631   OA
Spread of pedigree versus genetic ancestry in spatially distributed populations
J. Kelleher, A. Etheridge, A. Véber, N.H. Barton, Theoretical Population Biology 108 (2016) 1–12.
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2014 | Journal Article | IST-REx-ID: 1908   OA
The rate of adaptation in large sexual populations with linear chromosomes
D. Weissman, O. Hallatschek, Genetics 196 (2014) 1167–1183.
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2013 | Journal Article | IST-REx-ID: 2817   OA
Density games
S. Novak, K. Chatterjee, M. Nowak, Journal of Theoretical Biology 334 (2013) 26–34.
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2012 | Journal Article | IST-REx-ID: 2968   OA
A likelihood based comparison of population histories in a parasitoid guild
K. Lohse, N.H. Barton, G. Melika, G. Stone, Molecular Ecology 21 (2012) 4605–4617.
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2011 | Journal Article | IST-REx-ID: 3290   OA
A general method for calculating likelihoods under the coalescent process
K. Lohse, R. Harrison, N.H. Barton, Genetics 189 (2011) 977–987.
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2010 | Journal Article | IST-REx-ID: 3303   OA
The rate of fitness-valley crossing in sexual populations
D. Weissman, M. Feldman, D. Fisher, Genetics 186 (2010) 1389–1410.
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2011 | Journal Article | IST-REx-ID: 3391   OA
The contribution of statistical physics to evolutionary biology
H. de Vladar, N.H. Barton, Trends in Ecology and Evolution 26 (2011) 424–432.
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2018 | Journal Article | IST-REx-ID: 396
Inference from paternity and sibships accounting for uncertainty in genealogy
T. Ellis, D. Field, N.H. Barton, Molecular Ecology Resources 18 (2018) 988–999.
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2017 | Journal Article | IST-REx-ID: 1191   OA
Existence of traveling waves for the generalized F–KPP equation
R. Kollár, S. Novak, Bulletin of Mathematical Biology 79 (2017) 525–559.
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2016 | Journal Article | IST-REx-ID: 1420   OA
A general approximation for the dynamics of quantitative traits
K. Bod’ová, G. Tkacik, N.H. Barton, Genetics 202 (2016) 1523–1548.
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2015 | Journal Article | IST-REx-ID: 1519   OA
The interpretation of selection coefficients
N.H. Barton, M. Servedio, Evolution 69 (2015) 1101–1112.
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2015 | Journal Article | IST-REx-ID: 1850   OA View | Files available | DOI
 
2014 | Journal Article | IST-REx-ID: 1932   OA
Cryptic genetic variation can make "irreducible complexity" a common mode of adaptation in sexual populations
M. Trotter, D. Weissman, G. Peterson, K. Peck, J. Masel, Evolution 68 (2014) 3357–3367.
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2014 | Journal Article | IST-REx-ID: 2168   OA
Coalescent simulation in continuous space: Algorithms for large neighbourhood size
J. Kelleher, A. Etheridge, N.H. Barton, Theoretical Population Biology 95 (2014) 13–23.
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2013 | Journal Article | IST-REx-ID: 2473   OA
Genetic hitch-hiking in spatially extended populations
N.H. Barton, A. Etheridge, J. Kelleher, A. Véber, Theoretical Population Biology 87 (2013) 75–89.
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2013 | Conference Paper | IST-REx-ID: 2719
A variance decomposition approach to the analysis of genetic algorithms
T. Paixao, N.H. Barton, in:, Proceedings of the 15th Annual Conference on Genetic and Evolutionary Computation, ACM, 2013, pp. 845–852.
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2013 | Journal Article | IST-REx-ID: 2909   OA
Modelling evolution in a spatial continuum
N.H. Barton, A. Etheridge, A. Véber, Journal of Statistical Mechanics Theory and Experiment 2013 (2013).
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2012 | Journal Article | IST-REx-ID: 3166   OA
Amino acid fermentation at the origin of the genetic code
H. Vladar, Biology Direct 7 (2012).
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2011 | Journal Article | IST-REx-ID: 3394   OA
Genetic drift widens the expected cline but narrows the expected cline width
J. Polechova, N.H. Barton, Genetics 189 (2011) 227–235.
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2011 | Journal Article | IST-REx-ID: 3375   OA
The statistical mechanics of a polygenic character under stabilizing selection mutation and drift
H. de Vladar, N.H. Barton, Journal of the Royal Society Interface 8 (2011) 720–739.
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2018 | Journal Article | IST-REx-ID: 286
Efficient inference of paternity and sibship inference given known maternity via hierarchical clustering
T. Ellis, D. Field, N.H. Barton, Molecular Ecology Resources 18 (2018) 988–999.
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2015 | Journal Article | IST-REx-ID: 1576
Stochastic proofreading mechanism alleviates crosstalk in transcriptional regulation
S.A. Cepeda Humerez, G. Rieckh, G. Tkacik, Physical Review Letters 115 (2015).
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2017 | Journal Article | IST-REx-ID: 990   OA
Divergence and evolution of assortative mating in a polygenic trait model of speciation with gene flow
H. Sachdeva, N.H. Barton, Evolution; International Journal of Organic Evolution 71 (2017) 1478–1493.
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2017 | Journal Article | IST-REx-ID: 1063   OA View | DOI | Download (ext.)
 
2017 | Journal Article | IST-REx-ID: 1169   OA
Spatial gene frequency waves under genotype dependent dispersal
S. Novak, R. Kollár, Genetics 205 (2017) 367–374.
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2016 | Journal Article | IST-REx-ID: 1241   OA
The role of recombination in evolutionary rescue
H. Uecker, J. Hermisson, Genetics 202 (2016) 721–732.
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2016 | Journal Article | IST-REx-ID: 1195   OA
Reconstruction of haplotype-blocks selected during experimental evolution.
S. Franssen, N.H. Barton, C. Schlötterer, Molecular Biology and Evolution 34 (2016) 174–184.
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2016 | Journal Article | IST-REx-ID: 1359   OA
The effect of gene interactions on the long-term response to selection
T. Paixao, N.H. Barton, PNAS 113 (2016) 4422–4427.
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2016 | Journal Article | IST-REx-ID: 1518   OA
Efficient strategies for calculating blockwise likelihoods under the coalescent
K. Lohse, M. Chmelik, S. Martin, N.H. Barton, Genetics 202 (2016) 775–786.
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2014 | Journal Article | IST-REx-ID: 1936   OA
An arms race between producers and scroungers can drive the evolution of social cognition
M. Arbilly, D. Weissman, M. Feldman, U. Grodzinski, Behavioral Ecology 25 (2014) 487–495.
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2015 | Conference Paper | IST-REx-ID: 1835   OA
Model checking gene regulatory networks
M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, 9035 (2015) 469–483.
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2014 | Journal Article | IST-REx-ID: 2174   OA
Stability and response of polygenic traits to stabilizing selection and mutation
H. De Vladar, N.H. Barton, Genetics 197 (2014) 749–767.
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2013 | Conference Paper | IST-REx-ID: 2718   OA
Can quantitative and population genetics help us understand evolutionary computation?
N.H. Barton, T. Paixao, in:, Proceedings of the 15th Annual Conference on Genetic and Evolutionary Computation, ACM, 2013, pp. 1573–1580.
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2013 | Journal Article | IST-REx-ID: 2720   OA
Accumulation of spontaneous mutations in the ciliate Tetrahymena thermophila
H. Long, T. Paixao, R. Azevedo, R. Zufall, Genetics 195 (2013) 527–540.
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2013 | Journal Article | IST-REx-ID: 2910   OA
Coalescent simulation in continuous space
J. Kelleher, N.H. Barton, A. Etheridge, Bioinformatics 29 (2013) 955–956.
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2018 | Journal Article | IST-REx-ID: 564
Establishment in a new habitat by polygenic adaptation
N.H. Barton, A. Etheridge, Theoretical Population Biology 122 (2018) 110–127.
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2014 | Journal Article | IST-REx-ID: 2023 View | Files available | DOI