Cytoskeletal force generation and force transduction of migrating leukocytes

Project Period: 2011-08-01 – 2016-12-31
Externally Funded
Principal Investigator
Michael K Sixt
Department(s)
Sixt Group
Grant Number
Y 564-B12
Funding Organisation
FWF

8 Publications

2016 | Journal Article | IST-REx-ID: 1597   OA
Quantitative analysis of dendritic cell haptotaxis
J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.
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2016 | Journal Article | IST-REx-ID: 1285
Focal adhesion-independent cell migration
E. Paluch, I. Aspalter, M.K. Sixt, Annual Review of Cell and Developmental Biology 32 (2016) 469–490.
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2018 | Journal Article | IST-REx-ID: 402   OA
Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
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2016 | Journal Article | IST-REx-ID: 1599
Polysialylation controls dendritic cell trafficking by regulating chemokine recognition
E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy  Schahn, I. De Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190.
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2017 | Journal Article | IST-REx-ID: 672   OA
Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. De Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
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2016 | Journal Article | IST-REx-ID: 1154   OA
A microfluidic device for measuring cell migration towards substrate bound and soluble chemokine gradients
J. Schwarz, V. Bierbaum, J. Merrin, T. Frank, R. Hauschild, M.T. Bollenbach, S. Tay, M.K. Sixt, M. Mehling, Scientific Reports 6 (2016).
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2018 | Journal Article | IST-REx-ID: 275   OA
Lymphatic exosomes promote dendritic cell migration along guidance cues
M. Brown, L. Johnson, D. Leone, P. Májek, K. Vaahtomeri, D. Senfter, N. Bukosza, H. Schachner, G. Asfour, B. Langer, R. Hauschild, K. Parapatics, Y. Hong, K. Bennett, R. Kain, M. Detmar, M.K. Sixt, D. Jackson, D. Kerjaschki, Journal of Cell Biology 217 (2018) 2205–2221.
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2017 | Journal Article | IST-REx-ID: 674
Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. De Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
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