In situ real-time imaging of neurotransmitter signaling using designer optical sensors

Project Period: 2012-08-01 – 2016-01-31
Externally Funded
Principal Investigator
Harald L Janovjak
Department(s)
Janovjak Group
Grant Number
RGY0084/2012
Funding Organisation
HFSP

8 Publications

2018 | Journal Article | IST-REx-ID: 137   OA
Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS
W. Zhang, M. Herde, J. Mitchell, J. Whitfield, A. Wulff, V. Vongsouthi, I. Sanchez Romero, P. Gulakova, D. Minge, B. Breithausen, S. Schoch, H.L. Janovjak, C. Jackson, C. Henneberger, Nature Chemical Biology 14 (2018) 861–869.
View | DOI | Download (ext.) | PubMed | Europe PMC
 
2013 | Journal Article | IST-REx-ID: 2857   OA
Optical control of ligand-gated ion channels
S. Szobota, C. Mckenzie, H.L. Janovjak, Methods in Molecular Biology 998 (2013) 417–435.
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2017 | Journal Article | IST-REx-ID: 1026
Optogenetic methods in drug screening: Technologies and applications
V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.
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2015 | Journal Article | IST-REx-ID: 1867
Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection
J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, H.L. Janovjak, Electrophoresis 36 (2015) 518–525.
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2017 | Book Chapter | IST-REx-ID: 957
Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors
B. Clifton, J. Whitfield, I. Sanchez Romero, M. Herde, C. Henneberger, H.L. Janovjak, C. Jackson, in:, V. Stein (Ed.), Synthetic Protein Switches, Springer, 2017, pp. 71–87.
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2016 | Journal Article | IST-REx-ID: 1440 View | DOI
 
2015 | Journal Article | IST-REx-ID: 1611   OA
Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction
J. Whitfield, W. Zhang, M. Herde, B. Clifton, J. Radziejewski, H.L. Janovjak, C. Henneberger, C. Jackson, Protein Science 24 (2015) 1412–1422.
View | DOI | Download (ext.) | PubMed | Europe PMC
 
2015 | Journal Article | IST-REx-ID: 1678
Light-assisted small-molecule screening against protein kinases
Á. Inglés Prieto, E. Gschaider-Reichhart, M. Muellner, M. Nowak, S. Nijman, M. Grusch, H.L. Janovjak, Nature Chemical Biology 11 (2015) 952–954.
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