Alexander F Leithner
Sixt Group
9 Publications
2018 | Thesis | IST-REx-ID: 323 
Branched actin networks in dendritic cell biology
A.F. Leithner, Branched Actin Networks in Dendritic Cell Biology, IST Austria, 2018.
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| Files available
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A.F. Leithner, Branched Actin Networks in Dendritic Cell Biology, IST Austria, 2018.
2018 | Book Chapter | IST-REx-ID: 153
Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments
J. Renkawitz, A. Reversat, A.F. Leithner, J. Merrin, M.K. Sixt, in:, Methods in Cell Biology, Academic Press, 2018, pp. 79–91.
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| DOI
| PubMed | Europe PMC
J. Renkawitz, A. Reversat, A.F. Leithner, J. Merrin, M.K. Sixt, in:, Methods in Cell Biology, Academic Press, 2018, pp. 79–91.
2018 | Journal Article | IST-REx-ID: 437
Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration
A.F. Leithner, J. Renkawitz, I. De Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
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| Files available
| DOI
A.F. Leithner, J. Renkawitz, I. De Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
2018 | Journal Article | IST-REx-ID: 402
Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
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| Files available
| DOI
| Download (ext.)
| PubMed | Europe PMC
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
2018 | Journal Article | IST-REx-ID: 15
Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
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| Files available
| DOI
| Download (ext.)
| PubMed | Europe PMC
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
2017 | Research Data | IST-REx-ID: 5567
Immunological synapse DC-Tcells
A.F. Leithner, Immunological Synapse DC-Tcells, IST Austria, 2017.
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| Files available
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A.F. Leithner, Immunological Synapse DC-Tcells, IST Austria, 2017.
2017 | Journal Article | IST-REx-ID: 674
Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. De Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
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| DOI
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. De Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
2017 | Journal Article | IST-REx-ID: 672
Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. De Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
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| Files available
| DOI
K. Vaahtomeri, M. Brown, R. Hauschild, I. De Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
2016 | Journal Article | IST-REx-ID: 1321
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F. Schur, J. Bayerl, I. De Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
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| Files available
| DOI
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F. Schur, J. Bayerl, I. De Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
9 Publications
2018 | Thesis | IST-REx-ID: 323
Branched actin networks in dendritic cell biology
A.F. Leithner, Branched Actin Networks in Dendritic Cell Biology, IST Austria, 2018.
View
| Files available
| DOI
A.F. Leithner, Branched Actin Networks in Dendritic Cell Biology, IST Austria, 2018.
2018 | Book Chapter | IST-REx-ID: 153
Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments
J. Renkawitz, A. Reversat, A.F. Leithner, J. Merrin, M.K. Sixt, in:, Methods in Cell Biology, Academic Press, 2018, pp. 79–91.
View
| DOI
| PubMed | Europe PMC
J. Renkawitz, A. Reversat, A.F. Leithner, J. Merrin, M.K. Sixt, in:, Methods in Cell Biology, Academic Press, 2018, pp. 79–91.
2018 | Journal Article | IST-REx-ID: 437
Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration
A.F. Leithner, J. Renkawitz, I. De Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
View
| Files available
| DOI
A.F. Leithner, J. Renkawitz, I. De Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
2018 | Journal Article | IST-REx-ID: 402
Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
View
| Files available
| DOI
| Download (ext.)
| PubMed | Europe PMC
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
2018 | Journal Article | IST-REx-ID: 15
Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
View
| Files available
| DOI
| Download (ext.)
| PubMed | Europe PMC
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
2017 | Research Data | IST-REx-ID: 5567
Immunological synapse DC-Tcells
A.F. Leithner, Immunological Synapse DC-Tcells, IST Austria, 2017.
View
| Files available
| DOI
A.F. Leithner, Immunological Synapse DC-Tcells, IST Austria, 2017.
2017 | Journal Article | IST-REx-ID: 674
Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. De Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
View
| DOI
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. De Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
2017 | Journal Article | IST-REx-ID: 672
Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. De Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
View
| Files available
| DOI
K. Vaahtomeri, M. Brown, R. Hauschild, I. De Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
2016 | Journal Article | IST-REx-ID: 1321
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F. Schur, J. Bayerl, I. De Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
View
| Files available
| DOI
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F. Schur, J. Bayerl, I. De Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.